Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | TAS1R3 | Q7RTX0 | 4/20 | 0.37 |
| ▸ | TAS1R1 | Q7RTX1 | 4/20 | 0.37 |
| ▸ | TAS1R2 | Q8TE23 | 4/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | CRHR1 | P34998 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | PGK1 | P00558 | 1/20 | 0.33 |
| ▸ | PGK2 | P07205 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2497195 | 0.89 | HPGD (0.41) | KMT2AHPGDMEN1LMNASMN1; SMN2 | |
| SCHEMBL2064034 | 0.88 | ITGB1 (0.41) | KMT2AHPGDMEN1LMNASMN1; SMN2 | |
| SCHEMBL1035616 | 0.87 | KMT2A (0.40) | KMT2AHPGDMEN1LMNASMN1; SMN2 | |
| SCHEMBL6470163 | 0.86 | LPAR3 (0.40) | KMT2AHPGDMEN1LMNASMN1; SMN2 | |
| SCHEMBL6469685 | 0.86 | LPAR3 (0.40) | KMT2AHPGDMEN1LMNASMN1; SMN2 | |
| SCHEMBL28251245 | 0.86 | LPAR3 (0.40) | KMT2AHPGDMEN1LMNASMN1; SMN2 | |
| SCHEMBL8532958 | 0.86 | LPAR3 (0.40) | KMT2AHPGDMEN1LMNASMN1; SMN2 | |
| SCHEMBL6467886 | 0.86 | LPAR3 (0.40) | KMT2AHPGDMEN1LMNASMN1; SMN2 | |
| SCHEMBL5160037 | 0.85 | KMT2A (0.39) | KMT2AHPGDMEN1LMNASMN1; SMN2 | |
| SCHEMBL1029138 | 0.85 | KMT2A (0.39) | KMT2AHPGDMEN1LMNASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10023675-B2 | Polymer nanoparticles | ETH ZUERICH (CH) | 2018-07-17 | — | — | US | disclosed |
| US-20050096406-A1 | Reactive diluents and alkyd resin coating compositions | PRETOT ROGER (CH) | 2005-05-05 | — | — | US | disclosed |
| US-5534559-A | UNSATURATED POLYESTERS | CIBA-GEIGY CORPORATION (US) | 1996-07-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10023675-B2 | Polymer nanoparticles | POLQ, POLN, POLA1 | KMT2A 3225/4885HPGD 908/4885MEN1 2243/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.