Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.48 |
| ▸ | NPC1 | O15118 | 2/20 | 0.48 |
| ▸ | RAB9A | P51151 | 2/20 | 0.48 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.48 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.48 |
| ▸ | RELA | Q04206 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CXCR3 | P49682 | 3/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | DAO | P14920 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.38 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6806443 | 0.82 | ALDH1A1 (0.49) | MAPTALDH1A1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL8206338 | 0.82 | ALDH1A1 (0.49) | MAPTALDH1A1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL112394 | 0.82 | ALDH1A1 (0.49) | MAPTALDH1A1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL111084 | 0.82 | ALDH1A1 (0.49) | MAPTALDH1A1NPC1RAB9ASMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL3407515 | 0.81 | ALDH1A1 (0.48) | MAPTALDH1A1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL28561920 | 0.81 | ALDH1A1 (0.48) | MAPTALDH1A1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL1399903 | 0.80 | ALDH1A1 (0.50) | MAPTALDH1A1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL9419038 | 0.79 | ALDH1A1 (0.50) | ALDH1A1NPC1RAB9ASMN1; SMN2CXCR3 | |
| SCHEMBL12073747 | 0.78 | ESR1 (0.50) | MAPTALDH1A1CXCR3KDM4EKMT2A | |
| SCHEMBL21494752 | 0.78 | KMT2A (0.47) | MAPTALDH1A1NPC1RAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005049593-A2 | N-ACYLSULFONAMIDE APOPTOSIS PROMOTERS | ABBOTT LABORATORIES (US) | 2005-06-02 | — | — | WO | disclosed |