Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ANPEP | P15144 | 1/20 | 0.60 |
| ▸ | APAF1 | O14727 | 1/20 | 0.58 |
| ▸ | BCHE | P06276 | 1/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.53 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.53 |
| ▸ | HTR1A | P08908 | 1/20 | 0.53 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.53 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.53 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.53 |
| ▸ | SMPD1 | P17405 | 1/20 | 0.53 |
| ▸ | DRD1 | P21728 | 1/20 | 0.53 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.53 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.53 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.53 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.53 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.53 |
| ▸ | DRD3 | P35462 | 1/20 | 0.53 |
| ▸ | CASR | P41180 | 1/20 | 0.53 |
| ▸ | HTR2B | P41595 | 1/20 | 0.53 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18539372 | 0.86 | GBA1 (0.49) | ANPEPCYP1A2CYP2D6MEN1KMT2A | |
| SCHEMBL13673875 | 0.86 | GBA1 (0.49) | ANPEPCYP1A2CYP2D6MEN1KMT2A | |
| SCHEMBL17509718 | 0.86 | ANPEP (0.62) | ANPEPAPAF1BCHECYP3A4CHRM2 | |
| SCHEMBL21095164 | 0.82 | MEN1 (0.47) | ANPEPAPAF1BCHECYP3A4CHRM2 | |
| SCHEMBL30285806 | 0.82 | APAF1 (0.65) | ANPEPAPAF1BCHECYP3A4CHRM2 | |
| SCHEMBL5227140 | 0.81 | APAF1 (0.63) | ANPEPAPAF1BCHECYP3A4CHRM2 | |
| SCHEMBL5228652 | 0.81 | APAF1 (0.63) | ANPEPAPAF1BCHECYP3A4CHRM2 | |
| SCHEMBL26217022 | 0.81 | APAF1 (0.63) | ANPEPAPAF1BCHECYP3A4CHRM2 | |
| SCHEMBL7792066 | 0.79 | APAF1 (0.61) | ANPEPAPAF1BCHECYP3A4CHRM2 | |
| SCHEMBL11437811 | 0.78 | APAF1 (0.51) | ANPEPAPAF1ADRA2ALMNAGBA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005007625-A2 | HETEROCYCLIC AMIDES WITH ANTI-TUBERCULOSIS ACTIVITY | THE UNIVERSITY OF TENNESSEE RESEARCH FOUNDATION (US) | 2005-01-27 | — | — | WO | claimed |