Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASP2 | P42575 | 1/20 | 0.69 |
| ▸ | FAAH | O00519 | 4/20 | 0.68 |
| ▸ | NAAA | Q02083 | 1/20 | 0.65 |
| ▸ | DNM1 | Q05193 | 2/20 | 0.62 |
| ▸ | EPHX2 | P34913 | 3/20 | 0.59 |
| ▸ | SLC6A5 | Q9Y345 | 2/20 | 0.58 |
| ▸ | EPHX1 | P07099 | 4/20 | 0.53 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9126176 | 1.00 | CASP2 (0.69) | CASP2FAAHNAAADNM1EPHX2 | |
| SCHEMBL9125283 | 1.00 | CASP2 (0.69) | CASP2FAAHNAAADNM1EPHX2 | |
| SCHEMBL7773630 | 0.94 | CASP2 (0.60) | CASP2FAAHNAAADNM1EPHX2 | |
| SCHEMBL21234011 | 0.90 | CASP2 (0.83) | CASP2FAAHNAAADNM1EPHX2 | |
| SCHEMBL20542645 | 0.90 | CASP2 (0.83) | CASP2FAAHNAAADNM1EPHX2 | |
| SCHEMBL23775006 | 0.90 | CASP2 (0.83) | CASP2FAAHNAAADNM1EPHX2 | |
| SCHEMBL22271678 | 0.90 | CASP2 (0.83) | CASP2FAAHNAAADNM1EPHX2 | |
| SCHEMBL21633848 | 0.90 | CASP2 (0.83) | CASP2FAAHNAAADNM1EPHX2 | |
| SCHEMBL1456491 | 0.90 | CASP2 (0.83) | CASP2FAAHNAAADNM1EPHX2 | |
| SCHEMBL8745625 | 0.90 | CASP2 (0.83) | CASP2FAAHNAAADNM1EPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005037797-A1 | SUBSTITUTED PYRAZOLE UREA COMPOUNDS FOR THE TREATMENT OF INFLAMMATION | PHARMACIA CORPORATION (US) | 2005-04-28 | — | — | WO | claimed |