Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB2 | P07550 | 20/20 | 0.67 |
| ▸ | CHRM3 | P20309 | 20/20 | 0.67 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1256510 | 0.96 | ADRB2 (0.72) | ADRB2CHRM3 | |
| SCHEMBL1256513 | 0.96 | ADRB2 (0.72) | ADRB2CHRM3 | |
| SCHEMBL1256512 | 0.96 | ADRB2 (0.72) | ADRB2CHRM3 | |
| Fluoride SCHEMBL6364191 | 0.95 | ADRB2 (0.74) | ADRB2CHRM3 | |
| Fluoride Ion SCHEMBL6364188 | 0.93 | ADRB2 (0.73) | ADRB2CHRM3 | |
| SCHEMBL1256337 | 0.90 | ADRB2 (0.81) | ADRB2CHRM3 | |
| SCHEMBL1256339 | 0.90 | ADRB2 (0.81) | ADRB2CHRM3 | |
| SCHEMBL1256338 | 0.90 | ADRB2 (0.81) | ADRB2CHRM3 | |
| SCHEMBL1257183 | 0.89 | ADRB2 (0.82) | ADRB2CHRM3 | |
| SCHEMBL1257181 | 0.89 | ADRB2 (0.82) | ADRB2CHRM3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1592685-A1 | BIPHENYL DERIVATIVES HAVING &bgr; sb 2 /sb ADRENERGIC RECEPTOR AGONIST AND MUSCARINIC RECEPTOR ANTAGONIST ACTIVITY | Theravance Inc (US) | 2005-11-09 | — | — | EP | disclosed |
| WO-2004074276-A1 | BIPHENYL DERIVATIVES HAVING β2 ADRENERGIC RECEPTOR AGONIST AND MUSCARINIC RECEPTOR ANTAGONIST ACTIVITY | THERAVANCE INC. (US) | 2004-09-02 | — | — | WO | disclosed |