Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 2/20 | 0.41 |
| ▸ | CES1 | P23141 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 2/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4460608 | 0.94 | CES2 (0.48) | CES2CES1MAPK1 | |
| SCHEMBL5423235 | 0.92 | CES2 (0.52) | CES2CES1ALDH1A1MAPK1 | |
| SCHEMBL2935194 | 0.92 | CES2 (0.52) | CES2CES1ALDH1A1MAPK1 | |
| SCHEMBL758897 | 0.92 | CES2 (0.41) | CES2CES1ALDH1A1TP53 | |
| SCHEMBL10722450 | 0.88 | CES2 (0.52) | CES2CES1 | |
| SCHEMBL693122 | 0.88 | CES2 (0.52) | CES2CES1 | |
| SCHEMBL9119248 | 0.88 | CES2 (0.52) | CES2CES1 | |
| SCHEMBL2304845 | 0.88 | CES2 (0.52) | CES2CES1 | |
| SCHEMBL1692351 | 0.88 | CES2 (0.52) | CES2CES1 | |
| SCHEMBL7663036 | 0.88 | CES2 (0.52) | CES2CES1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005037797-A1 | SUBSTITUTED PYRAZOLE UREA COMPOUNDS FOR THE TREATMENT OF INFLAMMATION | PHARMACIA CORPORATION (US) | 2005-04-28 | — | — | WO | claimed |