Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 5/20 | 0.54 |
| ▸ | MAOA | P21397 | 3/20 | 0.54 |
| ▸ | RAB9A | P51151 | 4/20 | 0.50 |
| ▸ | MEN1 | O00255 | 3/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | NPC1 | O15118 | 3/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | PTPRC | P08575 | 1/20 | 0.43 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | HTR2C | P28335 | 1/20 | 0.42 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.39 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.39 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.39 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.39 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11768974 | 0.86 | MAOB (0.53) | MAOBMAOARAB9AMEN1KMT2A | |
| SCHEMBL11768960 | 0.86 | MAOB (0.53) | MAOBMAOARAB9AMEN1KMT2A | |
| SCHEMBL11332668 | 0.80 | MAOB (0.57) | MAOBMAOARAB9AMEN1KMT2A | |
| SCHEMBL2473793 | 0.80 | MAOB (0.57) | MAOBMAOARAB9AMEN1KMT2A | |
| SCHEMBL727203 | 0.78 | MAOB (0.62) | MAOBMAOARAB9AMEN1KMT2A | |
| SCHEMBL61411 | 0.77 | MAOB (0.71) | MAOBMAOARAB9AMEN1KMT2A | |
| SCHEMBL12854020 | 0.77 | MAOB (0.71) | MAOBMAOARAB9AMEN1KMT2A | |
| SCHEMBL7776816 | 0.74 | CSNK2A1 (0.46) | MAOBMAOARAB9AMEN1KMT2A | |
| SCHEMBL7776821 | 0.74 | CSNK2A1 (0.46) | MAOBMAOARAB9AMEN1KMT2A | |
| SCHEMBL6405539 | 0.72 | MEN1 (0.63) | MAOBMAOARAB9AMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005049593-A2 | N-ACYLSULFONAMIDE APOPTOSIS PROMOTERS | ABBOTT LABORATORIES (US) | 2005-06-02 | — | — | WO | disclosed |