SCHEMBL11768960

SCHEMBL11768960

C(=C/c1ccccc1-c1cc2ccccc2o1)\c1ccccc1

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAOB P27338 3/20 0.53
MAOA P21397 2/20 0.53
MEN1 O00255 4/20 0.46
KMT2A Q03164 4/20 0.46
RAB9A P51151 3/20 0.46
NPC1 O15118 3/20 0.45
POLB P06746 1/20 0.45
PTPRC P08575 1/20 0.42
PTPN1 P18031 1/20 0.42
APP P05067 1/20 0.41
HTR2C P28335 1/20 0.41
CYP3A4 P08684 1/20 0.40
ALOX5 P09917 1/20 0.40
TRPA1 O75762 1/20 0.40
RELA Q04206 1/20 0.40
NFE2L2 Q16236 1/20 0.40
TDP1 Q9NUW8 1/20 0.39
MAPT P10636 2/20 0.39
KDM4E B2RXH2 2/20 0.38
ALDH1A1 P00352 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11768974 1.00 MAOB (0.53) MAOBMAOAMEN1KMT2ARAB9A
SCHEMBL7776816 0.87 CSNK2A1 (0.46) MAOBMAOAMEN1KMT2ARAB9A
SCHEMBL7776821 0.87 CSNK2A1 (0.46) MAOBMAOAMEN1KMT2ARAB9A
SCHEMBL6470760 0.86 MAOB (0.54) MAOBMAOAMEN1KMT2ARAB9A
SCHEMBL7776794 0.80 KMT2A (0.45) MAOBMEN1KMT2ARAB9ANPC1
SCHEMBL7776787 0.80 KMT2A (0.45) MAOBMEN1KMT2ARAB9ANPC1
SCHEMBL28378590 0.80 RAB9A (0.48) MAOBMAOAMEN1KMT2ARAB9A
SCHEMBL11486060 0.79 MAOB (0.62) MAOBMAOAMEN1KMT2ARAB9A
SCHEMBL11332668 0.79 MAOB (0.57) MAOBMAOAMEN1KMT2ARAB9A
SCHEMBL11486058 0.79 MAOB (0.62) MAOBMAOAMEN1KMT2ARAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4013642-A OPTICAL BRIGHTENERS CIBA-GEIGY CORPORATION (US) 1977-03-22 US disclosed