Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | USP2 | O75604 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL50575 | 0.85 | — | — | |
| SCHEMBL12863650 | 0.85 | — | — | |
| SCHEMBL6433072 | 0.83 | LMNA (0.44) | LMNAALDH1A1TDP1TSHRUSP2 | |
| Glycerin SCHEMBL27514435 | 0.80 | LMNA (0.56) | LMNAALDH1A1TDP1TSHRL3MBTL1 | |
| SCHEMBL7151383 | 0.78 | LMNA (0.44) | LMNAALDH1A1TDP1TSHRL3MBTL1 | |
| SCHEMBL7595607 | 0.78 | LMNA (0.44) | LMNAALDH1A1TDP1TSHRL3MBTL1 | |
| SCHEMBL5919483 | 0.78 | LMNA (0.44) | LMNAALDH1A1TDP1TSHRL3MBTL1 | |
| SCHEMBL7150167 | 0.78 | LMNA (0.44) | LMNAALDH1A1TDP1TSHRL3MBTL1 | |
| SCHEMBL15484295 | 0.78 | TSHR (0.42) | TSHR | |
| SCHEMBL7151040 | 0.78 | LMNA (0.44) | LMNAALDH1A1TDP1TSHRL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050136108-A1 | Stepwise delivery of topiramate over prolonged period of time | YAM NOYMI V (US) | 2005-06-23 | — | — | US | disclosed |