Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 5/20 | 0.39 |
| ▸ | CA1 | P00915 | 4/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.34 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.34 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | LAP3 | P28838 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8446634 | 0.93 | CA2 (0.43) | CA2CA1USP2TSHRTDP1 | |
| SCHEMBL28255519 | 0.82 | CA2 (0.39) | CA2CA1USP2TSHRTDP1 | |
| Dimethylamine SCHEMBL28317955 | 0.80 | TDP1 (0.35) | CA2CA1TDP1KDM4E | |
| SCHEMBL4742989 | 0.80 | CA2 (0.47) | CA2CA1USP2TSHRTDP1 | |
| SCHEMBL733212 | 0.78 | CA1 (0.36) | CA2CA1USP2TSHRTDP1 | |
| SCHEMBL28817952 | 0.77 | CA1 (0.35) | CA2CA1USP2TSHRTDP1 | |
| SCHEMBL28420933 | 0.77 | CA2 (0.64) | CA2CA1USP2SLC1A3SLC1A2 | |
| SCHEMBL4861645 | 0.76 | TDP1 (0.35) | TDP1KDM4E | |
| SCHEMBL15846226 | 0.75 | CA2 (0.47) | CA2CA1MAPK1 | |
| SCHEMBL16245163 | 0.75 | CA2 (0.57) | CA2CA1SLC1A3SLC1A2SLC1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005054548-A2 | METHODS, COMPOSITIONS, AND KITS FOR PROTEIN CRYSTALLIZATION | INVITROGEN CORPORATION (US) | 2005-06-16 | — | — | WO | disclosed |