Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK14 | Q16539 | 19/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6471248 | 0.92 | MAPT (0.43) | MAPK14 | |
| SCHEMBL6473531 | 0.90 | HTT (0.41) | MAPK14 | |
| SCHEMBL6473704 | 0.90 | MAPK14 (0.44) | MAPK14 | |
| SCHEMBL6471546 | 0.87 | MAPK14 (0.44) | MAPK14 | |
| SCHEMBL6472713 | 0.86 | MAPK14 (0.55) | MAPK14 | |
| SCHEMBL6471322 | 0.84 | MAPK14 (0.44) | MAPK14 | |
| SCHEMBL6471941 | 0.83 | MAPK14 (0.46) | MAPK14 | |
| SCHEMBL6471639 | 0.83 | MAPK14 (0.43) | MAPK14 | |
| SCHEMBL6472442 | 0.82 | MAPK14 (0.57) | MAPK14 | |
| SCHEMBL6472921 | 0.82 | MAPK14 (0.45) | MAPK14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005018557-A2 | SUBSTITUTED PYRIDINONES | PHARMACIA CORPORATION (US) | 2005-03-03 | — | — | WO | disclosed |