Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | MAPK14 | Q16539 | 12/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.37 |
| ▸ | MAPK12 | P53778 | 1/20 | 0.37 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.37 |
| ▸ | STRADA | Q7RTN6 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6473704 | 0.91 | MAPK14 (0.44) | MAPK14POLBTSHRROCK2MAPK12 | |
| SCHEMBL6471248 | 0.91 | MAPT (0.43) | MAPK14POLBTSHR | |
| SCHEMBL6471190 | 0.90 | MAPK14 (0.45) | MAPK14 | |
| SCHEMBL6471546 | 0.88 | MAPK14 (0.44) | MAPK14POLBTSHRROCK2MAPK12 | |
| SCHEMBL6473656 | 0.87 | MAPK14 (0.47) | MAPK14ROCK2MAPK12MAPK11STRADA | |
| SCHEMBL6473278 | 0.85 | MAPK14 (0.42) | MAPK14 | |
| SCHEMBL6471587 | 0.83 | MAPK14 (0.46) | MAPK14 | |
| SCHEMBL6472377 | 0.82 | MAPK14 (0.47) | MAPK14ROCK2MAPK12MAPK11STRADA | |
| SCHEMBL6471706 | 0.81 | MAPK14 (0.45) | MAPK14ROCK2MAPK12MAPK11STRADA | |
| SCHEMBL6471420 | 0.81 | MAPK14 (0.38) | MAPK14ROCK2MAPK12MAPK11STRADA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005018557-A2 | SUBSTITUTED PYRIDINONES | PHARMACIA CORPORATION (US) | 2005-03-03 | — | — | WO | disclosed |