Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 3/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.51 |
| ▸ | CA12 | O43570 | 3/20 | 0.48 |
| ▸ | CA9 | Q16790 | 3/20 | 0.48 |
| ▸ | CA1 | P00915 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.48 |
| ▸ | HPGD | P15428 | 5/20 | 0.48 |
| ▸ | NPC1 | O15118 | 3/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | GLA | P06280 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | IGLV6-57 | P01721 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | ERAP2 | Q6P179 | 1/20 | 0.44 |
| ▸ | LNPEP | Q9UIQ6 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29823094 | 1.00 | RAB9A (0.54) | RAB9ATDP1CA12CA9CA1 | |
| SCHEMBL11465811 | 0.95 | KDM4E (0.51) | RAB9ATDP1CA12CA9CA1 | |
| SCHEMBL11462871 | 0.95 | KDM4E (0.51) | RAB9ATDP1CA12CA9CA1 | |
| Acetic Acid SCHEMBL1504306 | 0.91 | RAB9A (0.50) | RAB9ATDP1CA12CA9CA1 | |
| SCHEMBL29692701 | 0.91 | RAB9A (0.52) | RAB9ATDP1CA12CA9CA1 | |
| SCHEMBL29543699 | 0.91 | RAB9A (0.52) | RAB9ATDP1CA12CA9CA1 | |
| SCHEMBL30875001 | 0.91 | RAB9A (0.56) | RAB9ATDP1CA12CA9CA1 | |
| SCHEMBL7205667 | 0.90 | CA12 (0.52) | RAB9ATDP1CA12CA9CA1 | |
| SCHEMBL7205674 | 0.90 | CA12 (0.52) | RAB9ATDP1CA12CA9CA1 | |
| SCHEMBL7211984 | 0.89 | KDM4E (0.52) | RAB9ATDP1CA12CA9CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1601764-A2 | A CLASS OF METACASPASES | VIB vzw (BE) | 2005-12-07 | — | — | EP | disclosed |
| WO-2004081168-A2 | A CLASS OF METACASPASES | VIB VZW (BE) | 2004-09-23 | — | — | WO | disclosed |