Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGMT | P16455 | 4/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.36 |
| ▸ | MPO | P05164 | 1/20 | 0.36 |
| ▸ | TPO | P07202 | 1/20 | 0.36 |
| ▸ | EPX | P11678 | 1/20 | 0.36 |
| ▸ | DAPK1 | P53355 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.36 |
| ▸ | PHLPP2 | Q6ZVD8 | 1/20 | 0.36 |
| ▸ | CDK2 | P24941 | 2/20 | 0.35 |
| ▸ | CDK1 | P06493 | 1/20 | 0.35 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6472086 | 1.00 | MGMT (0.42) | MGMTALDH1A1KDM4EHPGDADRA1A | |
| SCHEMBL7886343 | 0.88 | MGMT (0.47) | MGMTALDH1A1CYP3A4MPOTPO | |
| SCHEMBL6476487 | 0.87 | MGMT (0.36) | MGMTALDH1A1KDM4EHPGDADRA1A | |
| SCHEMBL6476490 | 0.87 | MGMT (0.36) | MGMTALDH1A1KDM4EHPGDADRA1A | |
| SCHEMBL5508152 | 0.83 | KDM4E (0.45) | ALDH1A1KDM4EHPGDADRA1AHSD17B10 | |
| SCHEMBL5508144 | 0.83 | KDM4E (0.45) | ALDH1A1KDM4EHPGDADRA1AHSD17B10 | |
| SCHEMBL4572432 | 0.83 | KDM4E (0.47) | ALDH1A1KDM4EHPGDADRA1AHSD17B10 | |
| SCHEMBL5509446 | 0.82 | KDM4E (0.44) | ALDH1A1KDM4EHPGDADRA1AHSD17B10 | |
| SCHEMBL5509440 | 0.82 | KDM4E (0.44) | ALDH1A1KDM4EHPGDADRA1AHSD17B10 | |
| SCHEMBL4570456 | 0.80 | MGMT (0.47) | MGMTALDH1A1CYP3A4MPOTPO |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1535923-A1 | Synthesis of acyclic nucleoside derivatives | Medivir Aktiebolag (SE) | 2005-06-01 | — | — | EP | disclosed |