Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGMT | P16455 | 7/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.36 |
| ▸ | CDK1 | P06493 | 2/20 | 0.36 |
| ▸ | CCNB1 | P14635 | 2/20 | 0.36 |
| ▸ | CCNA2 | P20248 | 2/20 | 0.36 |
| ▸ | CDK2 | P24941 | 2/20 | 0.36 |
| ▸ | CCNA1 | P78396 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | MPO | P05164 | 1/20 | 0.36 |
| ▸ | TPO | P07202 | 1/20 | 0.36 |
| ▸ | EPX | P11678 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | BLM | P54132 | 1/20 | 0.36 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.36 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6476490 | 1.00 | MGMT (0.36) | MGMTCYP3A4CDK1CCNB1CCNA2 | |
| SCHEMBL6472086 | 0.87 | MGMT (0.42) | MGMTCYP3A4CDK1CCNB1CCNA2 | |
| SCHEMBL6472088 | 0.87 | MGMT (0.42) | MGMTCYP3A4CDK1CCNB1CCNA2 | |
| SCHEMBL6473315 | 0.83 | KDM4E (0.40) | ALDH1A1KDM4EHPGDADRA1AHSD17B10 | |
| SCHEMBL6473322 | 0.83 | KDM4E (0.40) | ALDH1A1KDM4EHPGDADRA1AHSD17B10 | |
| SCHEMBL8897365 | 0.76 | TSHR (0.43) | MGMTCYP3A4CDK1CCNB1CCNA2 | |
| SCHEMBL8898684 | 0.76 | MGMT (0.45) | MGMTCYP3A4CDK1CCNB1CCNA2 | |
| SCHEMBL7886343 | 0.74 | MGMT (0.47) | MGMTCYP3A4CDK1CCNB1CCNA2 | |
| SCHEMBL8896758 | 0.74 | MGMT (0.48) | MGMTCYP3A4CDK1CCNB1CCNA2 | |
| SCHEMBL5508144 | 0.72 | KDM4E (0.45) | ALDH1A1KDM4EHPGDADRA1AHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1535923-A1 | Synthesis of acyclic nucleoside derivatives | Medivir Aktiebolag (SE) | 2005-06-01 | — | — | EP | disclosed |