Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4B | Q07343 | 17/20 | 0.45 |
| ▸ | PDE4D | Q08499 | 5/20 | 0.43 |
| ▸ | PDE4A | P27815 | 3/20 | 0.43 |
| ▸ | PDE4C | Q08493 | 3/20 | 0.43 |
| ▸ | GFER | P55789 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6533416 | 0.89 | PDE4B (0.48) | PDE4BPDE4DPDE4APDE4CGFER | |
| SCHEMBL6472455 | 0.83 | PDE4B (0.46) | PDE4BPDE4DPDE4APDE4C | |
| SCHEMBL6471016 | 0.81 | PDE4B (0.42) | PDE4BPDE4DPDE4APDE4C | |
| SCHEMBL6471502 | 0.81 | PDE4B (0.46) | PDE4BPDE4DPDE4APDE4C | |
| SCHEMBL6470680 | 0.79 | KMT2A (0.44) | GFER | |
| SCHEMBL6472458 | 0.78 | PDE4B (0.44) | PDE4BPDE4DPDE4APDE4C | |
| SCHEMBL5016450 | 0.76 | PDE4D (0.57) | PDE4BPDE4DPDE4APDE4CGFER | |
| SCHEMBL6470780 | 0.75 | PDE4B (0.42) | PDE4BPDE4DPDE4APDE4C | |
| SCHEMBL6472450 | 0.73 | PDE4B (0.44) | PDE4BPDE4DPDE4APDE4C | |
| SCHEMBL5022391 | 0.73 | PDE4D (0.50) | PDE4BPDE4DPDE4APDE4CGFER |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1554262-A1 | NOVEL TRICYCLIC COMPOUNDS USEFUL FOR THE TREATMENT OF INFLAMMATORY AND ALLERGIC DISORDERS: PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | Glenmark Pharmaceuticals Limited (IN) | 2005-07-20 | — | — | EP | claimed |
| WO-2004037805-A1 | NOVEL TRICYCLIC COMPOUNDS USEFUL FOR THE TREATMENT OF INFLAMMATORY AND ALLERGIC DISORDERS: PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | GLENMARK PHARMACEUTICALS LTD. (US) | 2004-05-06 | — | — | WO | claimed |
| EP-1554262-A1 | NOVEL TRICYCLIC COMPOUNDS USEFUL FOR THE TREATMENT OF INFLAMMATORY AND ALLERGIC DISORDERS: PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | Glenmark Pharmaceuticals Limited (IN) | 2005-07-20 | — | — | EP | disclosed |
| WO-2004037805-A1 | NOVEL TRICYCLIC COMPOUNDS USEFUL FOR THE TREATMENT OF INFLAMMATORY AND ALLERGIC DISORDERS: PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | GLENMARK PHARMACEUTICALS LTD. (US) | 2004-05-06 | — | — | WO | disclosed |