SCHEMBL6472162

SCHEMBL6472162

Cc1cc(Br)c(C(F)(F)F)c(C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)F)c1Br

nearest known ligand 0.31

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2955275 0.77
SCHEMBL2956261 0.72
SCHEMBL2955920 0.69 LMNA (0.34) LMNA
SCHEMBL2966677 0.68 LMNA (0.37) LMNA
SCHEMBL27778733 0.67 APEX1 (0.36)
SCHEMBL674220 0.65 LMNA (0.42) LMNA
SCHEMBL10293003 0.65 LMNA (0.36) LMNA
SCHEMBL11995382 0.65 LMNA (0.36) LMNA
SCHEMBL13550089 0.63 HTT (0.37) LMNA
SCHEMBL13550080 0.63 HTT (0.34)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2005073338-A2 FLUORESCENT, SEMI-CONDUCTIVE POLYMERS, AND DEVICES COMPRISING THEM MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) 2005-08-11 WO disclosed