Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2D6 | P10635 | 3/20 | 0.54 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.54 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.54 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.54 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.54 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.54 |
| ▸ | TSHR | P16473 | 3/20 | 0.38 |
| ▸ | PMP22 | Q01453 | 2/20 | 0.38 |
| ▸ | GABRP | O00591 | 2/20 | 0.38 |
| ▸ | GABRD | O14764 | 2/20 | 0.38 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.38 |
| ▸ | GABRB1 | P18505 | 2/20 | 0.38 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.38 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.38 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.38 |
| ▸ | GABRA3 | P34903 | 2/20 | 0.38 |
| ▸ | GABRA2 | P47869 | 2/20 | 0.38 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.38 |
| ▸ | GABRA4 | P48169 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24690327 | 0.81 | CYP1A2 (0.33) | CYP2D6CYP2C19CYP1A2ALOX15SLC1A3 | |
| SCHEMBL24690311 | 0.81 | CYP1A2 (0.33) | CYP2D6CYP2C19CYP1A2ALOX15SLC1A3 | |
| SCHEMBL5749041 | 0.81 | CYP1A2 (0.33) | CYP2D6CYP2C19CYP1A2ALOX15SLC1A3 | |
| SCHEMBL24690458 | 0.81 | CYP1A2 (0.33) | CYP2D6CYP2C19CYP1A2ALOX15SLC1A3 | |
| SCHEMBL24690331 | 0.81 | CYP1A2 (0.33) | CYP2D6CYP2C19CYP1A2ALOX15SLC1A3 | |
| SCHEMBL5749038 | 0.78 | CYP1A2 (0.31) | CYP2D6CYP2C19CYP1A2ALOX15SLC1A3 | |
| SCHEMBL10591185 | 0.76 | CHRNB2 (0.47) | SMN1; SMN2 | |
| SCHEMBL1841417 | 0.76 | SLC1A2 (0.47) | CYP2D6CYP2C19CYP1A2ALOX15SLC1A3 | |
| SCHEMBL1841416 | 0.76 | SLC1A2 (0.47) | CYP2D6CYP2C19CYP1A2ALOX15SLC1A3 | |
| SCHEMBL1463849 | 0.76 | SLC1A2 (0.47) | CYP2D6CYP2C19CYP1A2ALOX15SLC1A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005112999-A2 | CANCER TREATMENT WITH INHIBITORS OF COLLAGEN SYNTHESIS | VECTRAMED, INC. (US) | 2005-12-01 | — | — | WO | disclosed |
| US-6346255-B1 | PAD FOR IMPROVING SKIN APPEARANCE WITH BACKING, RELEASE LAYERAND VEHICLE | LAVIPHARM LABORATORIES INC. | 2002-02-12 | — | — | US | disclosed |
| WO-1999036032-A1 | PLANT POLAR LIPID PERMEATION ENHANCER IN A COSMETIC PAD FOR IMPROVING SKIN APPEARANCE | LAVIPHARM LABORATORIES, INC. (US) | 1999-07-22 | — | — | WO | disclosed |
| EP-0740938-A3 | Proline and 4-hydroxyproline as therapeutic agents | IPR INST PHARM RES RIEHEN AG (CH) | 1997-03-12 | — | — | EP | disclosed |
| EP-0740938-A2 | Proline and 4-hydroxyproline as therapeutic agents | IPR-Institute for Pharmaceutical Research Riehen AG (CH) | 1996-11-06 | — | — | EP | disclosed |