Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK14 | Q16539 | 18/20 | 0.42 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.40 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.37 |
| ▸ | MAPK12 | P53778 | 1/20 | 0.37 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.37 |
| ▸ | STRADA | Q7RTN6 | 1/20 | 0.37 |
| ▸ | MAOB | P27338 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6471522 | 0.94 | MAPK14 (0.42) | MAPK14P2RX7ROCK2MAPK12MAPK11 | |
| SCHEMBL6474622 | 0.92 | MAPK14 (0.47) | MAPK14P2RX7 | |
| SCHEMBL6471307 | 0.92 | MAPK14 (0.48) | MAPK14P2RX7 | |
| SCHEMBL6472065 | 0.92 | MAPK14 (0.41) | MAPK14P2RX7ROCK2MAPK12MAPK11 | |
| SCHEMBL6471481 | 0.91 | P2RX7 (0.41) | MAPK14P2RX7ROCK2MAPK12MAPK11 | |
| Hydrochloric Acid SCHEMBL6474634 | 0.91 | P2RX7 (0.41) | MAPK14P2RX7ROCK2MAPK12MAPK11 | |
| Hydrochloric Acid SCHEMBL6472925 | 0.91 | MAPK14 (0.48) | MAPK14P2RX7ROCK2MAPK12MAPK11 | |
| SCHEMBL6473783 | 0.90 | MAPK14 (0.40) | MAPK14P2RX7ROCK2MAPK12MAPK11 | |
| Hydrochloric Acid SCHEMBL6473630 | 0.90 | MAPK14 (0.39) | MAPK14P2RX7ROCK2MAPK12MAPK11 | |
| SCHEMBL6471730 | 0.90 | CARM1 (0.41) | MAPK14P2RX7ROCK2MAPK12MAPK11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005018557-A2 | SUBSTITUTED PYRIDINONES | PHARMACIA CORPORATION (US) | 2005-03-03 | — | — | WO | claimed |
| WO-2005018557-A2 | SUBSTITUTED PYRIDINONES | PHARMACIA CORPORATION (US) | 2005-03-03 | — | — | WO | disclosed |