Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.60 |
| ▸ | LMNA | P02545 | 3/20 | 0.60 |
| ▸ | MEN1 | O00255 | 3/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.60 |
| ▸ | RAB9A | P51151 | 2/20 | 0.60 |
| ▸ | GAA | P10253 | 2/20 | 0.60 |
| ▸ | CASP3 | P42574 | 1/20 | 0.60 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.60 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.60 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.60 |
| ▸ | NPC1 | O15118 | 1/20 | 0.58 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.58 |
| ▸ | HTT | P42858 | 1/20 | 0.58 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.58 |
| ▸ | RELA | Q04206 | 1/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6473010 | 1.00 | MAPT (0.60) | MAPTLMNAMEN1ALDH1A1KMT2A | |
| SCHEMBL28482063 | 0.82 | THRB (0.46) | MAPTLMNAMEN1ALDH1A1KMT2A | |
| SCHEMBL9915661 | 0.81 | MAPT (0.87) | MAPTLMNAMEN1ALDH1A1KMT2A | |
| SCHEMBL11815668 | 0.81 | MAPT (0.87) | MAPTLMNAMEN1ALDH1A1KMT2A | |
| SCHEMBL11815663 | 0.81 | MAPT (0.87) | MAPTLMNAMEN1ALDH1A1KMT2A | |
| SCHEMBL22894912 | 0.79 | MAPT (0.64) | MAPTLMNAMEN1ALDH1A1KMT2A | |
| Hydrochloric Acid SCHEMBL11816321 | 0.79 | MAPT (0.84) | MAPTLMNAMEN1ALDH1A1KMT2A | |
| SCHEMBL20714497 | 0.79 | MAPT (0.55) | MAPTLMNAMEN1ALDH1A1KMT2A | |
| Hydrochloric Acid SCHEMBL11816315 | 0.79 | MAPT (0.84) | MAPTLMNAMEN1ALDH1A1KMT2A | |
| SCHEMBL3047673 | 0.79 | PLK1 (0.59) | MAPTLMNAMEN1ALDH1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230278952-A1 | Compounds Useful for Treating Liver Diseases | ABIONYX PHARMA SA (FR) | 2023-09-07 | — | — | US | disclosed |
| US-20210300890-A1 | Compounds Useful for Treating Liver Diseases | ABIONYX PHARMA SA (FR) | 2021-09-30 | — | — | US | disclosed |
| WO-2019025017-A1 | PROCESS FOR THE PREPARATION OF ELAFIBRANOR AND NOVEL SYNTHESIS INTERMEDIATES | ADVITECH ADVISORY AND TECHNOLOGIES SA (CH) | 2019-02-07 | — | — | WO | disclosed |
| WO-2005046650-A1 | PHARMACEUTICAL FORMULATION CONTAINING MUSCLE RELAXANT AND COX-II INHIBITOR | GLENMARK PHARMACEUTICALS LIMITED (US) | 2005-05-26 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230278952-A1 | Compounds Useful for Treating Liver Diseases | SLC10A1, FABP1, CPT1A | MAPT 4191/4885LMNA 1980/4885MEN1 4464/4885 |
| US-20210300890-A1 | Compounds Useful for Treating Liver Diseases | SLC10A1, FABP1, CPT1A | MAPT 4191/4885LMNA 1980/4885MEN1 4464/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.