Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 3/20 | 0.47 |
| ▸ | HPGD | P15428 | 10/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | PIM1 | P11309 | 2/20 | 0.46 |
| ▸ | PIM2 | Q9P1W9 | 2/20 | 0.46 |
| ▸ | IGF1R | P08069 | 1/20 | 0.46 |
| ▸ | MAOA | P21397 | 1/20 | 0.45 |
| ▸ | MAOB | P27338 | 1/20 | 0.45 |
| ▸ | GLS | O94925 | 1/20 | 0.44 |
| ▸ | GLS2 | Q9UI32 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6473102 | 0.88 | PTPN1 (0.49) | PTPN1HPGDMEN1POLBKMT2A | |
| SCHEMBL6473657 | 0.85 | PTPN1 (0.45) | PTPN1HPGDMEN1POLBKMT2A | |
| SCHEMBL6478125 | 0.85 | PTPN1 (0.45) | PTPN1HPGDMEN1POLBKMT2A | |
| SCHEMBL5386774 | 0.80 | MAOA (0.54) | PTPN1HPGDMEN1POLBKMT2A | |
| SCHEMBL5386765 | 0.80 | MAOA (0.54) | PTPN1HPGDMEN1POLBKMT2A | |
| SCHEMBL5397257 | 0.79 | PTPN1 (0.52) | PTPN1HPGDMEN1POLBKMT2A | |
| SCHEMBL6182142 | 0.77 | PIM1 (0.51) | PTPN1HPGDMEN1POLBKMT2A | |
| SCHEMBL6182139 | 0.77 | PIM1 (0.51) | PTPN1HPGDMEN1POLBKMT2A | |
| SCHEMBL6182857 | 0.77 | MEN1 (0.55) | PTPN1HPGDMEN1POLBKMT2A | |
| SCHEMBL6182863 | 0.77 | MEN1 (0.55) | PTPN1HPGDMEN1POLBKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6927228-B2 | Biphenyl compounds usefuf in treatment of human and veterinary medicines such as dermatology, cardivovascular diseases, immune diseases or diseases associated with lipid metabolisms, or in cosmetic formulation | GALDERMA RESEARCH & DEVELOPMENT, S.N.C. (FR) | 2005-08-09 | — | — | US | disclosed |