SCHEMBL6473199

SCHEMBL6473199

CCC1CCC(O)=C(O)C1

nearest known ligand 0.43

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
NOS3 P29474 3/20 0.43
NOS1 P29475 3/20 0.43
NOS2 P35228 3/20 0.43
ALDH1A1 P00352 2/20 0.34
MAPT P10636 2/20 0.34
GAA P10253 1/20 0.34
HPGD P15428 1/20 0.34
POLB P06746 1/20 0.31
TDP1 Q9NUW8 1/20 0.31
AIP O00170 1/20 0.31
SGTA O43765 1/20 0.31
TOMM70 O94826 1/20 0.31
STIP1 P31948 1/20 0.31
PPP5C P53041 1/20 0.31
DNAJC7 Q99615 1/20 0.31
STUB1 Q9UNE7 1/20 0.31
FYN P06241 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13772719 0.82 NOS3 (0.38) NOS3NOS1NOS2ALDH1A1MAPT
SCHEMBL12345281 0.78 CYP1A2 (0.45) NOS3NOS1NOS2ALDH1A1MAPT
SCHEMBL858020 0.75 MAPT (0.39) NOS3NOS1NOS2ALDH1A1MAPT
SCHEMBL858019 0.75 MAPT (0.39) NOS3NOS1NOS2ALDH1A1MAPT
SCHEMBL28239639 0.70
SCHEMBL6440092 0.70
SCHEMBL1523518 0.70
SCHEMBL2688028 0.70 NOS3 (0.43) NOS3NOS1NOS2ALDH1A1MAPT
SCHEMBL6438413 0.70
SCHEMBL27383074 0.70

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2012008508-A1 HETEROCYCLIC RING COMPOUND 武田薬品工業株式会社 (JP) 2012-01-19 WO disclosed
WO-2005050311-A1 STABILIZED HIGH-SPEED EMULSIONS AND PHOTOTHERMOGRAPHIC MATERIALS EASTMAN KODAK COMPANY (US) 2005-06-02 WO disclosed