Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.40 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.30 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.30 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.30 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6473315 | 1.00 | KDM4E (0.40) | KDM4EALDH1A1HPGDADRA1AHSD17B10 | |
| SCHEMBL5508152 | 0.84 | KDM4E (0.45) | KDM4EALDH1A1HPGDADRA1AHSD17B10 | |
| SCHEMBL5508144 | 0.84 | KDM4E (0.45) | KDM4EALDH1A1HPGDADRA1AHSD17B10 | |
| SCHEMBL6476490 | 0.83 | MGMT (0.36) | KDM4EALDH1A1HPGDADRA1AHSD17B10 | |
| SCHEMBL6476487 | 0.83 | MGMT (0.36) | KDM4EALDH1A1HPGDADRA1AHSD17B10 | |
| SCHEMBL3155510 | 0.80 | KDM4E (0.58) | KDM4EALDH1A1HPGDADRA1AHSD17B10 | |
| SCHEMBL4572432 | 0.78 | KDM4E (0.47) | KDM4EALDH1A1HPGDADRA1AHSD17B10 | |
| SCHEMBL5509440 | 0.78 | KDM4E (0.44) | KDM4EALDH1A1HPGDADRA1AHSD17B10 | |
| SCHEMBL5509446 | 0.78 | KDM4E (0.44) | KDM4EALDH1A1HPGDADRA1AHSD17B10 | |
| SCHEMBL4570455 | 0.76 | KDM4E (0.44) | KDM4EALDH1A1HPGDADRA1AHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1535923-A1 | Synthesis of acyclic nucleoside derivatives | Medivir Aktiebolag (SE) | 2005-06-01 | — | — | EP | disclosed |