Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C9 | P11712 | 2/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.42 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.42 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | PARP1 | P09874 | 4/20 | 0.39 |
| ▸ | DPP4 | P27487 | 1/20 | 0.39 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.39 |
| ▸ | RBP4 | P02753 | 2/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | DRD2 | P14416 | 1/20 | 0.36 |
| ▸ | CCR8 | P51685 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6471735 | 0.88 | CYP2D6 (0.53) | CYP2C9L3MBTL1CYP3A4CYP2D6CYP2C19 | |
| SCHEMBL6441424 | 0.87 | L3MBTL1 (0.49) | CYP2C9L3MBTL1CYP3A4CYP2D6KCNH2 | |
| SCHEMBL6442045 | 0.87 | CYP2C9 (0.56) | CYP2C9L3MBTL1CYP3A4CYP2D6KCNH2 | |
| SCHEMBL6443089 | 0.84 | L3MBTL1 (0.46) | CYP2C9L3MBTL1CYP3A4CYP2D6KCNH2 | |
| SCHEMBL6443079 | 0.82 | L3MBTL1 (0.46) | CYP2C9L3MBTL1CYP3A4CYP2D6KCNH2 | |
| SCHEMBL6471347 | 0.81 | CYP2C9 (0.51) | CYP2C9CYP3A4CYP2D6KCNH2CYP1A2 | |
| SCHEMBL6442530 | 0.80 | L3MBTL1 (0.43) | CYP2C9L3MBTL1CYP3A4CYP2D6KCNH2 | |
| SCHEMBL6443103 | 0.79 | L3MBTL1 (0.42) | CYP2C9L3MBTL1CYP3A4CYP2D6KCNH2 | |
| SCHEMBL6442104 | 0.78 | CYP2C9 (0.53) | CYP2C9L3MBTL1CYP3A4CYP2D6KCNH2 | |
| SCHEMBL6441836 | 0.78 | L3MBTL1 (0.41) | CYP2C9L3MBTL1CYP3A4CYP2D6KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1299382-B1 | COMPOSITION AND ANTIVIRAL ACTIVITY OF SUBSTITUTED INDOLEOXOACETIC PIPERAZINE DERIVATIVES | BRISTOL MYERS SQUIBB CO (US) | 2005-09-21 | — | — | EP | claimed |