Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK14 | Q16539 | 15/20 | 0.41 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.39 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.39 |
| ▸ | GABRP | O00591 | 1/20 | 0.35 |
| ▸ | GABRD | O14764 | 1/20 | 0.35 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.35 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.35 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.35 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.35 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.35 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.35 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.35 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.35 |
| ▸ | GABRA4 | P48169 | 1/20 | 0.35 |
| ▸ | GABRE | P78334 | 1/20 | 0.35 |
| ▸ | GABRA6 | Q16445 | 1/20 | 0.35 |
| ▸ | GABRG1 | Q8N1C3 | 1/20 | 0.35 |
| ▸ | GABRG3 | Q99928 | 1/20 | 0.35 |
| ▸ | GABRQ | Q9UN88 | 1/20 | 0.35 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6471998 | 0.91 | MAPK14 (0.43) | MAPK14PTGER1ROCK2MAPK12MAPK11 | |
| SCHEMBL6471283 | 0.90 | PDE3B (0.37) | MAPK14PDE3BPDE3AGABRPGABRD | |
| SCHEMBL6471970 | 0.89 | MAPK14 (0.44) | MAPK14PTGER1ROCK2MAPK12MAPK11 | |
| SCHEMBL6472398 | 0.88 | MAPK14 (0.43) | MAPK14PTGER1 | |
| SCHEMBL6471447 | 0.87 | MAPK14 (0.43) | MAPK14 | |
| SCHEMBL6474519 | 0.86 | MAPK14 (0.46) | MAPK14ROCK2MAPK12MAPK11STRADA | |
| SCHEMBL6474965 | 0.85 | MAPK14 (0.39) | MAPK14ROCK2MAPK12MAPK11STRADA | |
| SCHEMBL6471472 | 0.85 | MAPK14 (0.43) | MAPK14 | |
| SCHEMBL6472626 | 0.85 | MAPK14 (0.40) | MAPK14ROCK2MAPK12MAPK11STRADA | |
| SCHEMBL6471303 | 0.85 | MAPK14 (0.41) | MAPK14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005018557-A2 | SUBSTITUTED PYRIDINONES | PHARMACIA CORPORATION (US) | 2005-03-03 | — | — | WO | disclosed |