SCHEMBL6471472

SCHEMBL6471472

Cc1[nH]c(=O)c(Br)c(OCc2ccc(F)cc2F)c1Cc1cnc(CN)cn1

nearest known ligand 0.43

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
MAPK14 Q16539 20/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6471447 0.89 MAPK14 (0.43) MAPK14
SCHEMBL6471998 0.87 MAPK14 (0.43) MAPK14
Hydrochloric Acid SCHEMBL6472925 0.87 MAPK14 (0.48) MAPK14
SCHEMBL6474622 0.87 MAPK14 (0.47) MAPK14
SCHEMBL6471385 0.87 MAPK14 (0.41) MAPK14
SCHEMBL6471522 0.87 MAPK14 (0.42) MAPK14
SCHEMBL6472890 0.86 MAPK14 (0.42) MAPK14
SCHEMBL6471970 0.86 MAPK14 (0.44) MAPK14
SCHEMBL6473585 0.85 MAPK14 (0.41) MAPK14
SCHEMBL6472398 0.85 MAPK14 (0.43) MAPK14

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2005018557-A2 SUBSTITUTED PYRIDINONES PHARMACIA CORPORATION (US) 2005-03-03 WO disclosed