Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABL1 | P00519 | 8/20 | 0.62 |
| ▸ | BCR | P11274 | 8/20 | 0.62 |
| ▸ | TRPV1 | Q8NER1 | 4/20 | 0.55 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | CDK1 | P06493 | 1/20 | 0.51 |
| ▸ | P2RY14 | Q15391 | 1/20 | 0.47 |
| ▸ | QPCT | Q16769 | 3/20 | 0.46 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | USP2 | O75604 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | GLA | P06280 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4832960 | 0.83 | ABL1 (0.72) | ABL1BCRTRPV1MEN1USP2 | |
| SCHEMBL6033075 | 0.80 | MAPT (0.52) | MAPTCDK1P2RY14QPCTS1PR1 | |
| SCHEMBL4837361 | 0.79 | ABL1 (0.74) | ABL1BCRTRPV1S1PR1MEN1 | |
| SCHEMBL4837497 | 0.78 | TRPV1 (0.76) | ABL1BCRTRPV1MEN1USP2 | |
| SCHEMBL15534046 | 0.78 | ABL1 (0.68) | ABL1BCRTRPV1MAPTMEN1 | |
| SCHEMBL1016320 | 0.78 | ABL1 (0.76) | ABL1BCRTRPV1MEN1USP2 | |
| SCHEMBL1013728 | 0.78 | ABL1 (0.76) | ABL1BCRTRPV1MEN1USP2 | |
| SCHEMBL12943121 | 0.77 | ABL1 (1.00) | ABL1BCRTRPV1MEN1USP2 | |
| SCHEMBL1012574 | 0.77 | ABL1 (0.75) | ABL1BCRTRPV1MAPTMEN1 | |
| SCHEMBL4832759 | 0.76 | TRPV1 (0.87) | ABL1BCRTRPV1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050197342-A1 | Substituted nitrogen-containing six-membered amino-heterocycles as vanilloid-1 receptor antagonists for treating pain | HOLLINGWORTH GREGORY J (GB) | 2005-09-08 | — | — | US | claimed |
| US-20050197342-A1 | Substituted nitrogen-containing six-membered amino-heterocycles as vanilloid-1 receptor antagonists for treating pain | HOLLINGWORTH GREGORY J (GB) | 2005-09-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050197342-A1 | Substituted nitrogen-containing six-membered amino-heterocycles as vanilloid-1 receptor antagonists for treating pain | OPRL1, OPRK1, CNR1 | ABL1 989/4885BCR 1760/4885TRPV1 11/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.