Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 4/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 4/20 | 0.44 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.44 |
| ▸ | GLA | P06280 | 1/20 | 0.44 |
| ▸ | IDE | P14735 | 1/20 | 0.44 |
| ▸ | XBP1 | P17861 | 1/20 | 0.44 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.44 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | MITF | O75030 | 2/20 | 0.42 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6408766 | 1.00 | MAPK1 (0.46) | MAPK1ALDH1A1MAPTNPSR1HCRTR1 | |
| SCHEMBL6407542 | 0.97 | ALDH1A1 (0.46) | MAPK1ALDH1A1MAPTNPSR1HCRTR1 | |
| SCHEMBL6413599 | 0.93 | ALDH1A1 (0.49) | MAPK1ALDH1A1MAPTNPSR1HPGD | |
| SCHEMBL6406774 | 0.88 | MAPK1 (0.45) | MAPK1ALDH1A1MAPTNPSR1HCRTR1 | |
| SCHEMBL6407075 | 0.88 | MAPK1 (0.45) | MAPK1ALDH1A1MAPTNPSR1HCRTR1 | |
| SCHEMBL6407554 | 0.87 | MAPK1 (0.44) | MAPK1ALDH1A1MAPTNPSR1HCRTR1 | |
| SCHEMBL6408824 | 0.87 | MAPK1 (0.44) | MAPK1ALDH1A1MAPTNPSR1HCRTR1 | |
| SCHEMBL6408275 | 0.83 | TRPV1 (0.45) | MAPK1ALDH1A1MAPTNPSR1HCRTR1 | |
| SCHEMBL6412548 | 0.83 | TRPV1 (0.45) | MAPK1ALDH1A1MAPTNPSR1HCRTR1 | |
| SCHEMBL6474528 | 0.81 | MAPK1 (0.47) | MAPK1ALDH1A1MAPTNPSR1HCRTR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1538141-A1 | PROCESS FOR PRODUCTION OF 2-(HYDROXYMETHYL)CYCLO- PROPANECARBOXYLIC ACIDS | Sumitomo Chemical Company, Limited (JP) | 2005-06-08 | — | — | EP | disclosed |