SCHEMBL6474029

SCHEMBL6474029

NC(Cc1ccccc1)C(=O)NCC(=O)NC(Cc1ccccc1)C(=O)NCC(=O)O

nearest known ligand 0.64

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
OPRD1 P41143 10/20 0.64
OPRM1 P35372 8/20 0.64
OPRK1 P41145 2/20 0.64
CTSL P07711 1/20 0.51
CTSB P07858 1/20 0.51
CTSS P25774 1/20 0.51
MME P08473 2/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6474035 1.00 OPRD1 (0.64) OPRD1OPRM1OPRK1CTSLCTSB
SCHEMBL30100565 0.94 OPRD1 (0.73) OPRD1OPRM1OPRK1
SCHEMBL21010207 0.92 OPRD1 (0.64) OPRD1OPRM1OPRK1CTSLCTSB
SCHEMBL30637561 0.92 OPRD1 (0.70) OPRD1OPRM1OPRK1
SCHEMBL29505897 0.92 OPRD1 (0.70) OPRD1OPRM1OPRK1
SCHEMBL30865865 0.92 OPRD1 (0.70) OPRD1OPRM1OPRK1
SCHEMBL17430646 0.92 OPRD1 (0.70) OPRD1OPRM1OPRK1
SCHEMBL30637530 0.92 OPRD1 (0.70) OPRD1OPRM1OPRK1
SCHEMBL30637587 0.92 OPRD1 (0.70) OPRD1OPRM1OPRK1
SCHEMBL30051754 0.91 OPRD1 (0.59) OPRD1OPRM1OPRK1CTSSMME

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 229 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116660543-A Diagnostic and prognostic markers for nonalcoholic fatty liver disease and uses thereof 中国人民解放军陆军军医大学第一附属医院 2023-08-29 CN claimed
CN-1254379-A Method for producing amidated peptides by using fusion proteins PPL THERAPEUTICS SCOTLAND LTD (GB) 2000-05-24 CN claimed
EP-0979291-A1 METHODS OF PRODUCTION OF AN AMIDATED PEPTIDE THROUGH THE USE OF A FUSION PROTEIN PPL Therapeutics (Scotland) Limited (GB) 2000-02-16 EP claimed
WO-1998050563-A1 METHODS OF PRODUCTION OF AN AMIDATED PEPTIDE THROUGH THE USE OF A FUSION PROTEIN PPL THERAPEUTICS (SCOTLAND) LTD. (GB) 1998-11-12 WO claimed
CN-113710807-B Microorganisms and methods for producing oxygenates from hexoses 布拉斯科公司 2025-05-30 CN disclosed
CN-112601808-B Microorganism producing eicosapentaenoic acid and process for producing eicosapentaenoic acid 协和发酵生化株式会社 2025-05-02 CN disclosed
CN-114126665-B Gene therapy for yellow spot disease of ocular fundus (ABCA 4) 马萨诸塞大学 2025-04-25 CN disclosed
CN-114540456-B Method for resolution of methyl 2- (benzyloxycarbonylamino) -2- (oxetan-3-yl) acetate 弈柯莱生物科技(集团)股份有限公司 2025-04-22 CN disclosed
CN-111973738-B Nucleic acid and recombinant protein co-immune vaccine based on classical swine fever virus gene, preparation method and application 天康生物制药有限公司 2025-04-18 CN disclosed
US-20250122515-A1 COMPOSITIONS AND METHODS FOR INCREASING PLANT GROWTH AND IMPROVING MULTIPLE YIELD-RELATED TRAITS AFINGEN, INC. (US) 2025-04-17 US disclosed
CN-112740044-B Method for diagnosis or prognosis of neurological disorders 阿尔斯特创新有限公司 2025-04-11 CN disclosed
CN-114867739-B Fusion polypeptides comprising GDF15 and a polypeptide domain capable of O-glycosylation 株式会社LG化学 2025-04-08 CN disclosed
EP-0884389-A1 Enzyme participating in C-terminal amidation, and method of preparing same and use thereof SHISEIDO COMPANY LIMITED (JP) 1998-12-16 EP disclosed
WO-1998050563-A1 METHODS OF PRODUCTION OF AN AMIDATED PEPTIDE THROUGH THE USE OF A FUSION PROTEIN PPL THERAPEUTICS (SCOTLAND) LTD. (GB) 1998-11-12 WO disclosed
EP-0438600-B1 ENZYMES WHICH PARTICIPATE IN C-TERMINAL AMIDATION, AND PRODUCTION AND USE THEREOF SHISEIDO CO LTD (JP) 1996-02-07 EP disclosed
EP-0666318-A1 Enzyme participating in c-terminal amidation, and method of preparing same and use thereof SHISEIDO COMPANY LIMITED (JP) 1995-08-09 EP disclosed
US-5354675-A Amidation of glycine SHISEIDO COMPANY LTD. (JP) 1994-10-11 US disclosed
EP-0447547-B1 C-TERMINUS AMIDATION ENZYME COMPOSITION, PROCESS FOR ITS PREPARATION AND ITS USE SHISEIDO CO LTD (JP) 1994-07-27 EP disclosed
EP-0447547-A1 C-TERMINUS AMIDATION ENZYME COMPOSITION, PROCESS FOR ITS PREPARATION AND ITS USE SHISEIDO COMPANY LIMITED (JP) 1991-09-25 EP disclosed
EP-0438600-A1 ENZYMES WHICH PARTICIPATE IN C-TERMINAL AMIDATION, AND PRODUCTION AND USE THEREOF SHISEIDO COMPANY LIMITED (JP) 1991-07-31 EP disclosed