Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 1/20 | 0.62 |
| ▸ | RXRA | P19793 | 2/20 | 0.53 |
| ▸ | RXRB | P28702 | 2/20 | 0.53 |
| ▸ | KIF11 | P52732 | 3/20 | 0.52 |
| ▸ | DHODH | Q02127 | 1/20 | 0.51 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.49 |
| ▸ | SLC13A5 | Q86YT5 | 1/20 | 0.49 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.49 |
| ▸ | PTPN5 | P54829 | 2/20 | 0.47 |
| ▸ | BACE1 | P56817 | 1/20 | 0.47 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.46 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.45 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.45 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.45 |
| ▸ | MGLL | Q99685 | 1/20 | 0.45 |
| ▸ | RXRG | P48443 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5791295 | 0.94 | KIF11 (0.55) | APPRXRARXRBKIF11DHODH | |
| SCHEMBL6472732 | 0.84 | KIF11 (0.51) | APPRXRARXRBKIF11DHODH | |
| SCHEMBL1626915 | 0.83 | APP (0.55) | APPMGLL | |
| SCHEMBL16087802 | 0.80 | KIF11 (0.65) | RXRARXRBKIF11DHODHPTPN1 | |
| SCHEMBL4597367 | 0.79 | APP (0.78) | APPMAP4K4BACE1 | |
| SCHEMBL16068255 | 0.79 | KIF11 (0.67) | KIF11DHODHPTPN1 | |
| SCHEMBL1626471 | 0.79 | APP (0.62) | APPPTPN1 | |
| SCHEMBL3726479 | 0.78 | KIF11 (0.55) | RXRARXRBKIF11DHODHPTPN1 | |
| SCHEMBL5790943 | 0.78 | KIF11 (0.55) | RXRARXRBKIF11SLC13A5BACE1 | |
| SCHEMBL894000 | 0.77 | SLC13A5 (0.52) | RXRARXRBKIF11DHODHSLC13A5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005110963-A1 | (BIPHENYL-3-YL)-CARBOXYLIC ACIDS AND DERIVATIVES THEREOF AND THEIR USE IN THERAPY | CELLZOME AG (DE) | 2005-11-24 | — | — | WO | disclosed |