Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SERPINE1 | P05121 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 7/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.45 |
| ▸ | MAPT | P10636 | 5/20 | 0.45 |
| ▸ | LMNA | P02545 | 3/20 | 0.45 |
| ▸ | BLM | P54132 | 2/20 | 0.45 |
| ▸ | NPC1 | O15118 | 2/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.45 |
| ▸ | TSHR | P16473 | 2/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.45 |
| ▸ | THPO | P40225 | 2/20 | 0.45 |
| ▸ | PMP22 | Q01453 | 2/20 | 0.45 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | CDK2 | P24941 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.45 |
| ▸ | RECQL | P46063 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6474797 | 0.83 | KMT2A (0.59) | SERPINE1MEN1KMT2AMAPTLMNA | |
| SCHEMBL6482234 | 0.82 | KMT2A (0.60) | SERPINE1MEN1KMT2AMAPTLMNA | |
| SCHEMBL6475459 | 0.80 | KMT2A (0.60) | SERPINE1MEN1KMT2AMAPTLMNA | |
| SCHEMBL6474969 | 0.78 | KMT2A (0.66) | SERPINE1MEN1KMT2AMAPTLMNA | |
| SCHEMBL6484266 | 0.77 | MEN1 (0.46) | SERPINE1MEN1KMT2AMAPTLMNA | |
| SCHEMBL6474565 | 0.75 | MEN1 (0.50) | SERPINE1MEN1KMT2AMAPTLMNA | |
| SCHEMBL6474556 | 0.74 | CTSV (0.51) | SERPINE1MEN1KMT2AMAPTLMNA | |
| SCHEMBL6486672 | 0.74 | MEN1 (0.66) | SERPINE1MEN1KMT2AMAPTLMNA | |
| SCHEMBL4206812 | 0.73 | MAPT (0.72) | SERPINE1MEN1KMT2AMAPTLMNA | |
| SCHEMBL6474815 | 0.71 | MEN1 (0.54) | SERPINE1MEN1KMT2AMAPTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6972287-B1 | Method of inhibiting amyloid protein aggregation and imaging amyloid deposits | PFIZER INC. (US) | 2005-12-06 | — | — | US | claimed |
| US-6972287-B1 | Method of inhibiting amyloid protein aggregation and imaging amyloid deposits | PFIZER INC. (US) | 2005-12-06 | — | — | US | disclosed |