Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARD | Q03181 | 5/20 | 0.51 |
| ▸ | PPARA | Q07869 | 4/20 | 0.51 |
| ▸ | PPARG | P37231 | 3/20 | 0.51 |
| ▸ | SRD5A2 | P31213 | 4/20 | 0.48 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | S1PR1 | P21453 | 2/20 | 0.43 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.41 |
| ▸ | NDUFS8 | O00217 | 1/20 | 0.41 |
| ▸ | COXFA4 | O00483 | 1/20 | 0.41 |
| ▸ | NDUFAB1 | O14561 | 1/20 | 0.41 |
| ▸ | NDUFA1 | O15239 | 1/20 | 0.41 |
| ▸ | NDUFS4 | O43181 | 1/20 | 0.41 |
| ▸ | NDUFB5 | O43674 | 1/20 | 0.41 |
| ▸ | NDUFB3 | O43676 | 1/20 | 0.41 |
| ▸ | NDUFC1 | O43677 | 1/20 | 0.41 |
| ▸ | NDUFA2 | O43678 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6474921 | 1.00 | PPARD (0.51) | PPARDPPARAPPARGSRD5A2RAB9A | |
| SCHEMBL6474934 | 1.00 | PPARD (0.51) | PPARDPPARAPPARGSRD5A2RAB9A | |
| SCHEMBL6474300 | 0.89 | SRD5A2 (0.62) | PPARDPPARAPPARGSRD5A2S1PR1 | |
| SCHEMBL6474294 | 0.89 | SRD5A2 (0.62) | PPARDPPARAPPARGSRD5A2S1PR1 | |
| SCHEMBL6474305 | 0.89 | SRD5A2 (0.62) | PPARDPPARAPPARGSRD5A2S1PR1 | |
| SCHEMBL6474206 | 0.82 | PPARD (0.55) | PPARDPPARAPPARGSRD5A2RAB9A | |
| SCHEMBL6474209 | 0.82 | PPARD (0.55) | PPARDPPARAPPARGSRD5A2RAB9A | |
| SCHEMBL6474200 | 0.82 | PPARD (0.55) | PPARDPPARAPPARGSRD5A2RAB9A | |
| SCHEMBL3192546 | 0.82 | SRD5A2 (0.58) | SRD5A2MAPK14NPC1ALDH1A1EPHX2 | |
| SCHEMBL9239800 | 0.79 | NDUFS8 (0.43) | PPARDPPARAPPARGRAB9AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6869967-B2 | Peroxisome proliferator-activated receptor (PPAR) active vinyl carboxylic acid derivatives | NOVO NORDISK A/S (DK) | 2005-03-22 | — | — | US | claimed |
| EP-1414778-A1 | NOVEL VINYL CARBOXYLIC ACID DERIVATIVES AND THEIR USE AS ANTIDIABETICS ETC. | NOVO NORDISK A/S (DK) | 2004-05-06 | — | — | EP | claimed |
| US-20030139473-A1 | Novel compounds, their preparation and use | VTVX HOLDINGS II LLC | 2003-07-24 | — | — | US | claimed |
| WO-2003011807-A1 | NOVEL VINYL CARBOXYLIC ACID DERIVATIVES AND THEIR USE AS ANTIDIABETICS ETC. | NOVO NORDISK A/S (DK) | 2003-02-13 | — | — | WO | claimed |
| US-6869967-B2 | Peroxisome proliferator-activated receptor (PPAR) active vinyl carboxylic acid derivatives | NOVO NORDISK A/S (DK) | 2005-03-22 | — | — | US | disclosed |
| EP-1414778-A1 | NOVEL VINYL CARBOXYLIC ACID DERIVATIVES AND THEIR USE AS ANTIDIABETICS ETC. | NOVO NORDISK A/S (DK) | 2004-05-06 | — | — | EP | disclosed |
| US-20030139473-A1 | Novel compounds, their preparation and use | VTVX HOLDINGS II LLC | 2003-07-24 | — | — | US | disclosed |
| WO-2003011807-A1 | NOVEL VINYL CARBOXYLIC ACID DERIVATIVES AND THEIR USE AS ANTIDIABETICS ETC. | NOVO NORDISK A/S (DK) | 2003-02-13 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030139473-A1 | Novel compounds, their preparation and use | PPARG, PPARD, PPARA | PPARD 2/4885PPARA 3/4885PPARG 1/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.