Sugi Predict

Sugi Predict / Compounds / SCHEMBL6475566

SCHEMBL6475566

SCHEMBL6475566

CC(C)[C@H](N)C(=O)OC1CCC(C(=O)OCOP(=O)(O)C(O)(CCCN)P(=O)(O)OCOC(=O)C2CCC(OC(=O)[C@@H](N)C(C)C)CC2)CC1

nearest known ligand 0.32

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
▸ FDPS P14324 1/20 0.32
▸ PDE3A Q14432 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3739851 0.95 FDPS (0.30) FDPSPDE3A
SCHEMBL3729904 0.90 FDPS (0.36) FDPSPDE3A
SCHEMBL7862907 0.77 FDPS (0.47) FDPSPDE3A
SCHEMBL5994556 0.76 FDPS (0.37) FDPSPDE3A
SCHEMBL5995956 0.76 FDPS (0.37) FDPSPDE3A
SCHEMBL7861919 0.71 FDPS (0.40) FDPSPDE3A
SCHEMBL7862915 0.71 FDPS (0.40) FDPSPDE3A
SCHEMBL7855065 0.70 FDPS (0.40) FDPSPDE3A
SCHEMBL7861872 0.70 FDPS (0.40) FDPSPDE3A
SCHEMBL7862033 0.70 FDPS (0.50) FDPSPDE3A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6974802-B2 Treatment of viral infections using prodrugs of 2′,3-dideoxy,3′-fluoroguanosine MEDIVIR AB (SE) 2005-12-13 — — US disclosed