SCHEMBL647632

SCHEMBL647632

O=C(OC(=O)c1ccncc1)c1ccncc1

nearest known ligand 0.64

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HSD17B10 Q99714 1/20 0.64
NAPRT Q6XQN6 1/20 0.56
CYP1A2 P05177 2/20 0.53
CYP2C19 P33261 2/20 0.53
LMNA P02545 2/20 0.53
CYP2C9 P11712 1/20 0.53
SMN1; SMN2 Q16637 1/20 0.53
ALDH1A1 P00352 1/20 0.52
KMT2A Q03164 2/20 0.50
MEN1 O00255 1/20 0.50
L3MBTL1 Q9Y468 1/20 0.50
KDM4E B2RXH2 4/20 0.48
RAB9A P51151 2/20 0.48
NPC1 O15118 1/20 0.48
GLA P06280 1/20 0.48
TSHR P16473 1/20 0.48
MPO P05164 1/20 0.48
CYP3A4 P08684 1/20 0.48
ADORA3 P0DMS8 1/20 0.48
CYP2D6 P10635 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11665942 0.91 KMT2A (0.65) HSD17B10NAPRTCYP1A2CYP2C19LMNA
SCHEMBL28108729 0.88 HSD17B10 (0.57) HSD17B10NAPRTCYP1A2CYP2C19LMNA
SCHEMBL3292573 0.86 HSD17B10 (0.55) HSD17B10NAPRTCYP1A2CYP2C19LMNA
SCHEMBL6877560 0.86 HSD17B10 (0.55) HSD17B10NAPRTCYP1A2CYP2C19LMNA
SCHEMBL112786 0.86 HSD17B10 (0.55) HSD17B10NAPRTCYP1A2CYP2C19LMNA
SCHEMBL28838030 0.84 HSD17B10 (0.53) HSD17B10NAPRTCYP1A2CYP2C19LMNA
SCHEMBL27430724 0.84 ALDH1A1 (0.62) CYP1A2CYP2C19LMNACYP2C9ALDH1A1
SCHEMBL20599732 0.83 CYP1A2 (0.53) HSD17B10NAPRTCYP1A2CYP2C19LMNA
SCHEMBL28160711 0.83 HSD17B10 (0.52) HSD17B10NAPRTCYP1A2CYP2C19LMNA
SCHEMBL14393318 0.83 HSD17B10 (0.52) HSD17B10NAPRTCYP1A2CYP2C19LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 105 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118925800-A Acid modified supported COFs catalyst and preparation method and application thereof 浙江工业大学 2024-11-12 CN claimed
US-11788080-B2 Modified cleavases, uses thereof and related kits Encodia, Inc. (US) 2023-10-17 US claimed
US-20230257727-A1 MODIFIED CLEAVASES, USES THEREOF AND RELATED KITS Encodia, Inc. (US) 2023-08-17 US claimed
CN-113930215-B High-elasticity-recovery-rate cracking material silicone sealant and preparation method thereof 湖北回天新材料(宜城)有限公司 2023-04-11 CN claimed
US-11427814-B2 Modified cleavases, uses thereof and related kits Encodia, Inc. (US) 2022-08-30 US claimed
EP-3947667-A1 MODIFIED CLEAVASES, USES THEREOF AND RELATED KITS Encodia, Inc. (US) 2022-02-09 EP claimed
CN-113993997-A Modified cleaving enzymes, uses thereof and related kits ENCODIA 公司 2022-01-28 CN claimed
CN-113930215-A High-elasticity-recovery-rate cracking material silicone sealant and preparation method thereof 湖北回天新材料(宜城)有限公司 2022-01-14 CN claimed
US-20210214701-A1 MODIFIED CLEAVASES, USES THEREOF AND RELATED KITS Encodia, Inc. (US) 2021-07-15 US claimed
WO-2020198264-A1 MODIFIED CLEAVASES, USES THEREOF AND RELATED KITS Encodia, Inc. (US) 2020-10-01 WO claimed
US-20120283089-A1 ZIEGLER-NATTA CATALYST FOR OLEFIN POLYMERIZATION HYOSUNG CORPORATION (KR) 2012-11-08 US claimed
EP-2520594-A2 ZIEGLER-NATTA CATALYST FOR OLEFIN POLYMERIZATION Hyosung Corporation (KR) 2012-11-07 EP claimed
US-6113678-A Hot melt inks containing polyanhydrides XEROX CORPORATION (US) 2000-09-05 US claimed
EP-0332579-B1 Method for protecting plants from diseases CIBA GEIGY AG (CH) 1994-08-10 EP claimed
EP-0334813-B1 Agents for the protection of plants against diseases CIBA GEIGY AG (CH) 1994-02-02 EP claimed
EP-4127157-B1 MODIFIED DIPEPTIDE CLEAVASES, USES THEREOF AND RELATED KITS ENCODIA INC (US) 2026-02-11 EP disclosed
CN-118925800-A Acid modified supported COFs catalyst and preparation method and application thereof 浙江工业大学 2024-11-12 CN disclosed
US-3969523-A Antiphlogistic pharmaceutical compositions containing a 1-(nicotinoyl or isonicotinoyl)-3-biphenylyl-alkanone-(2) BOEHRINGER INGELHEIM GMBH (DT) 1976-07-13 US disclosed
US-3969419-A ANTIPHLOGISTIC BOEHRINGER INGELHEIM GMBH (DT) 1976-07-13 US disclosed
US-3936465-A SURFACTANT, WATER SOFTENER, BACTERICIDE, HYPOTENSIVE E. R. SQUIBB & SONS, INC. (US) 1976-02-03 US disclosed