Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.46 |
| ▸ | LMNA | P02545 | 5/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 4/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | MAPT | P10636 | 4/20 | 0.46 |
| ▸ | WDR5 | P61964 | 3/20 | 0.46 |
| ▸ | ENGASE | Q8NFI3 | 3/20 | 0.46 |
| ▸ | DDAH1 | O94760 | 2/20 | 0.46 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | TBXA2R | P21731 | 2/20 | 0.46 |
| ▸ | NPY1R | P25929 | 2/20 | 0.46 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.46 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.46 |
| ▸ | HTR3A | P46098 | 2/20 | 0.46 |
| ▸ | FASN | P49327 | 2/20 | 0.46 |
| ▸ | SARM1 | Q6SZW1 | 2/20 | 0.46 |
| ▸ | ABCG2 | Q9UNQ0 | 2/20 | 0.46 |
| ▸ | HTR1A | P08908 | 1/20 | 0.46 |
| ▸ | IDE | P14735 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9025509 | 0.99 | KMT2A (0.45) | KMT2ALMNACYP2C9ALDH1A1MAPT | |
| SCHEMBL9025491 | 0.99 | KMT2A (0.45) | KMT2ALMNACYP2C9ALDH1A1MAPT | |
| SCHEMBL8542308 | 0.95 | KMT2A (0.49) | KMT2ALMNACYP2C9ALDH1A1MAPT | |
| SCHEMBL8502421 | 0.91 | KMT2A (0.45) | KMT2ALMNACYP2C9ALDH1A1MAPT | |
| SCHEMBL8503518 | 0.91 | KMT2A (0.52) | KMT2ALMNACYP2C9ALDH1A1MAPT | |
| SCHEMBL9022527 | 0.91 | KMT2A (0.48) | KMT2ALMNACYP2C9ALDH1A1MAPT | |
| SCHEMBL13871335 | 0.91 | CYP2C9 (0.46) | KMT2ALMNACYP2C9ALDH1A1MAPT | |
| SCHEMBL8503064 | 0.90 | KMT2A (0.44) | KMT2ALMNACYP2C9ALDH1A1MAPT | |
| SCHEMBL8526311 | 0.90 | ALDH1A1 (0.43) | KMT2ALMNACYP2C9ALDH1A1MAPT | |
| SCHEMBL5352982 | 0.90 | KMT2A (0.54) | KMT2ALMNACYP2C9ALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5945425-A | ADENOSINE TRIPHOSPHASE INHIBITOR; DNA VIRICIDE | G.D. SEARLE & CO. (US) | 1999-08-31 | — | — | US | claimed |
| US-6906078-B2 | Method of using (H+/K+) ATPase inhibitors as antiviral agents | PHARMACIA CORPORATION (US) | 2005-06-14 | — | — | US | disclosed |
| US-5945425-A | ADENOSINE TRIPHOSPHASE INHIBITOR; DNA VIRICIDE | G.D. SEARLE & CO. (US) | 1999-08-31 | — | — | US | disclosed |