Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.51 |
| ▸ | MAPT | P10636 | 2/20 | 0.51 |
| ▸ | TP53 | P04637 | 2/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.51 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
| ▸ | BLM | P54132 | 1/20 | 0.51 |
| ▸ | CASP7 | P55210 | 1/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.51 |
| ▸ | TNFRSF1A | P19438 | 3/20 | 0.41 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.38 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.38 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | MITF | O75030 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | XDH | P47989 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1406850 | 0.93 | MAPT (0.46) | SMN1; SMN2MAPTTP53CYP3A4ALOX15 | |
| SCHEMBL1406634 | 0.91 | SMN1; SMN2 (0.53) | SMN1; SMN2MAPTTP53CYP3A4ALOX15 | |
| SCHEMBL1406635 | 0.91 | SMN1; SMN2 (0.53) | SMN1; SMN2MAPTTP53CYP3A4ALOX15 | |
| SCHEMBL1406825 | 0.87 | MAPT (0.50) | SMN1; SMN2MAPTTP53CYP3A4ALOX15 | |
| SCHEMBL1407067 | 0.85 | MAPT (0.52) | SMN1; SMN2MAPTTP53CYP3A4ALOX15 | |
| SCHEMBL1407068 | 0.85 | MAPT (0.52) | SMN1; SMN2MAPTTP53CYP3A4ALOX15 | |
| SCHEMBL1406556 | 0.84 | MAPT (0.47) | SMN1; SMN2MAPTTP53CYP3A4ALOX15 | |
| SCHEMBL1406751 | 0.84 | MAPT (0.47) | SMN1; SMN2MAPTTP53CYP3A4ALOX15 | |
| SCHEMBL1406706 | 0.82 | SMN1; SMN2 (0.53) | SMN1; SMN2MAPTTP53CYP3A4ALOX15 | |
| SCHEMBL1406717 | 0.82 | SMN1; SMN2 (0.53) | SMN1; SMN2MAPTTP53CYP3A4ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050131033-A1 | Novel ligand inhibitors of the RAR receptors, process for preparing same and therapeutic/cosmetic applications thereof | GALDERMA RESEARCH & DEVELOPMENT, S.N.C. (FR) | 2005-06-16 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050131033-A1 | Novel ligand inhibitors of the RAR receptors, process for preparing same and therapeutic/cosmetic applications thereof | RARA, RARB, RARG | SMN1; SMN2 4756/4885MAPT 4711/4885TP53 427/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.