Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Adipic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | FABP4 | P15090 | 1/20 | 0.39 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.38 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.38 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.38 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.38 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.38 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.38 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.38 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.38 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.38 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.38 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27571608 | 0.87 | POLB (0.42) | TSHRPOLBMAPTHDAC3HDAC4 | |
| Adipic Acid SCHEMBL9058463 | 0.86 | TSHR (0.42) | TSHRMEN1KMT2ALMNAFABP4 | |
| Adipic Acid SCHEMBL8533918 | 0.83 | TSHR (0.46) | TSHRLMNANFKB1PMP22MAPT | |
| SCHEMBL23668109 | 0.78 | POLB (0.62) | TSHRMEN1KMT2APOLBLMNA | |
| SCHEMBL29568597 | 0.78 | POLB (0.62) | TSHRMEN1KMT2APOLBLMNA | |
| Hydrochloric Acid SCHEMBL3105189 | 0.76 | POLB (0.59) | TSHRMEN1KMT2APOLBLMNA | |
| Water SCHEMBL28687155 | 0.76 | POLB (0.59) | TSHRMEN1KMT2APOLBLMNA | |
| Hydrochloric Acid SCHEMBL4608951 | 0.76 | POLB (0.59) | TSHRMEN1KMT2APOLBLMNA | |
| Ammonia Solution, Strong SCHEMBL18426057 | 0.76 | POLB (0.59) | TSHRMEN1KMT2APOLBLMNA | |
| Butyric Acid SCHEMBL21957825 | 0.75 | FFAR3 (0.46) | TSHRMEN1KMT2APOLBMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 46 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2255978-B1 | LAMINATE AND PNEUMATIC TIRE USING THE LAMINATE | YOKOHAMA RUBBER CO LTD (JP) | 2013-02-27 | — | — | EP | claimed |
| US-20110011507-A1 | LAMINATE AND PNEUMATIC TIRE USING THE LAMINATE | THE YOKOHAMA RUBBER CO., LTD. (JP) | 2011-01-20 | — | — | US | claimed |
| EP-2255978-A1 | LAMINATE AND PNEUMATIC TIRE USING THE LAMINATE | The Yokohama Rubber Co., Ltd. (JP) | 2010-12-01 | — | — | EP | claimed |
| US-11283043-B2 | Laminated film and process for manufacturing the same | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2022-03-22 | — | — | US | disclosed |
| US-11038145-B2 | Laminated film and process for manufacturing the same, as well as method for analyzing laminated film | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2021-06-15 | — | — | US | disclosed |
| US-20180000727-A1 | COMPOSITION AND METHODS TO IMPROVE STABILITY, DOSING, PHARMACODYNAMICS AND PRODUCT SHELF LIFE OF ENDOCANNABINOIDS, PHYTOCANNABINOIDS AND SYNTHETIC CANNABINOIDS DELIVERED BY NASAL INHAER | WILLINSKY MICHAEL (CA) | 2018-01-04 | — | — | US | disclosed |
| US-9850371-B2 | Methods for producing resin film and layered article | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2017-12-26 | — | — | US | disclosed |
| EP-3247402-A1 | COMPOSITION AND METHODS TO IMPROVE STABILITY, DOSING, PHARMACODYNAMICS AND PRODUCT SHELF LIFE OF ENDOCANNABINOIDS, PHYTOCANNABINOIDS AND SYNTHETIC CANNABINOIDS DELIVERED BY NASAL INHALER | Willinsky, Michael (CA) | 2017-11-29 | — | — | EP | disclosed |
| US-20170288171-A1 | LAMINATED FILM AND PROCESS FOR MANUFACTURING THE SAME | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2017-10-05 | — | — | US | disclosed |
| US-20170288170-A1 | LAMINATED FILM AND PROCESS FOR MANUFACTURING THE SAME | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2017-10-05 | — | — | US | disclosed |
| US-20170288169-A1 | LAMINATED FILM AND PROCESS FOR MANUFACTURING THE SAME, AS WELL AS METHOD FOR ANALYZING LAMINATED FILM | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2017-10-05 | — | — | US | disclosed |
| EP-0778153-B1 | Laminated film produced by gravure coating | SUMITOMO CHEMICAL CO (JP) | 1999-08-11 | — | — | EP | disclosed |
| EP-0691376-B1 | RESIN COMPOSITION, LAMINATE, AND LAMINATED FILM | SUMITOMO CHEMICAL CO (JP) | 1999-08-04 | — | — | EP | disclosed |
| US-5869573-A | COMPRISING A POLYAMINOAMIDE AND A SAPONIFIED ETHYLENE-VINYL ESTER COPOLYMER | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1999-02-09 | — | — | US | disclosed |
| US-5700560-A | HYDROGEN BONDING RESIN, CLAY; FOOD PACKAGING; STORAGE STABILITY | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1997-12-23 | — | — | US | disclosed |
| EP-0780431-A1 | Resin composition and shaped article having a layer comprising the same | SUMITOMO CHEMICAL COMPANY LIMITED (JP) | 1997-06-25 | — | — | EP | disclosed |
| EP-0778153-A1 | Laminated film produced by gravure coating | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1997-06-11 | — | — | EP | disclosed |
| EP-0691202-A1 | LAMINATE, LAMINATED FILM AND MOLDING | SUMITOMO CHEMICAL COMPANY LIMITED (JP) | 1996-01-10 | — | — | EP | disclosed |
| EP-0691376-A1 | RESIN COMPOSITION, LAMINATE, AND LAMINATED FILM | SUMITOMO CHEMICAL COMPANY LIMITED (JP) | 1996-01-10 | — | — | EP | disclosed |
| EP-0590263-A2 | Gas barrier resin composition and process for producing the same | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1994-04-06 | — | — | EP | disclosed |