Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Adipic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | FABP4 | P15090 | 2/20 | 0.39 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.38 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.38 |
| ▸ | HDAC11 | Q96DB2 | 3/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.38 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.38 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.38 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.38 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.38 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.38 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.38 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.38 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.38 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Adipic Acid SCHEMBL647718 | 0.86 | TSHR (0.46) | TSHRLMNAFABP4NFKB1PMP22 | |
| SCHEMBL34364 | 0.78 | POLB (0.48) | TSHRMAPTTDP1ALDH1A1ALOX15 | |
| SCHEMBL29366969 | 0.78 | POLB (0.48) | TSHRMAPTTDP1ALDH1A1ALOX15 | |
| Hydrochloric Acid SCHEMBL5183951 | 0.76 | POLB (0.46) | TSHRLMNAMAPTTDP1ALDH1A1 | |
| Adipic Acid SCHEMBL8533918 | 0.76 | TSHR (0.46) | TSHRLMNANFKB1PMP22HDAC11 | |
| Phthalic Acid SCHEMBL9869587 | 0.75 | ALDH1A1 (0.50) | LMNAMEN1KMT2AAKR1B1TDP1 | |
| Butyric Acid SCHEMBL21957825 | 0.75 | FFAR3 (0.46) | TSHRMAPTHDAC3HDAC1HDAC2 | |
| Sulfuric Acid SCHEMBL30338570 | 0.75 | ALDH1A1 (0.39) | TSHRMAPTMEN1KMT2ATDP1 | |
| Dodecane SCHEMBL28198074 | 0.73 | SKP2 (0.44) | TSHRLMNAMAPTTDP1ALDH1A1 | |
| SCHEMBL27571608 | 0.73 | POLB (0.42) | TSHRHDAC11MAPTHDAC3HDAC4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1996011861-A1 | OXYGEN SCAVENGING ARTICLE FOR USE IN PACKAGES | CHEVRON CHEMICAL COMPANY (US) | 1996-04-25 | — | — | WO | claimed |