Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DUSP3 | P51452 | 2/20 | 0.52 |
| ▸ | ADORA2A | P29274 | 12/20 | 0.49 |
| ▸ | ADORA2B | P29275 | 12/20 | 0.49 |
| ▸ | ADORA1 | P30542 | 12/20 | 0.49 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL3050899 | 0.99 | DUSP3 (0.51) | DUSP3ADORA2AADORA2BADORA1CHRM4 | |
| SCHEMBL6476277 | 0.94 | DUSP3 (0.53) | DUSP3ADORA2AADORA2BADORA1CHRM4 | |
| Hydrochloric Acid SCHEMBL3045899 | 0.93 | DUSP3 (0.53) | DUSP3ADORA2AADORA2BADORA1CHRM4 | |
| SCHEMBL6484767 | 0.93 | DUSP3 (0.50) | DUSP3ADORA2AADORA2BADORA1CHRM4 | |
| Hydrochloric Acid SCHEMBL3039089 | 0.92 | DUSP3 (0.49) | DUSP3ADORA2AADORA2BADORA1CHRM4 | |
| SCHEMBL3055622 | 0.92 | DUSP3 (0.51) | DUSP3ADORA2AADORA2BADORA1CHRM4 | |
| Hydrochloric Acid SCHEMBL3058132 | 0.91 | DUSP3 (0.50) | DUSP3ADORA2AADORA2BADORA1CHRM4 | |
| SCHEMBL3057471 | 0.91 | DUSP3 (0.50) | DUSP3ADORA2AADORA2BADORA1CHRM4 | |
| SCHEMBL3047875 | 0.91 | CHRM4 (0.57) | DUSP3ADORA2AADORA2BADORA1CHRM4 | |
| Hydrochloric Acid SCHEMBL3044579 | 0.90 | DUSP3 (0.49) | DUSP3ADORA2AADORA2BADORA1CHRM4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6963000-B2 | Benzothiazole derivatives with activity as adenosine receptor ligands | HOFFMAN-LA ROCHE INC. (US) | 2005-11-08 | — | — | US | claimed |