Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNA7 | P36544 | 7/20 | 0.61 |
| ▸ | CHRNB2 | P17787 | 5/20 | 0.39 |
| ▸ | CHRNA4 | P43681 | 5/20 | 0.39 |
| ▸ | HTR3A | P46098 | 2/20 | 0.39 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.39 |
| ▸ | HTR3B | O95264 | 1/20 | 0.39 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.39 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.39 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.38 |
| ▸ | CHRNB4 | P30926 | 3/20 | 0.36 |
| ▸ | CHRNA3 | P32297 | 3/20 | 0.36 |
| ▸ | CNR2 | P34972 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL373301 | 0.97 | CHRNA7 (0.64) | CHRNA7CHRNB2CHRNA4HTR3AHTR3E | |
| Fumaric Acid SCHEMBL1542643 | 0.89 | CHRNA7 (0.55) | CHRNA7CHRNB2CHRNA4HTR3AHTR3E | |
| Fumaric Acid SCHEMBL1542650 | 0.89 | CHRNA7 (0.55) | CHRNA7CHRNB2CHRNA4HTR3AHTR3E | |
| SCHEMBL1542416 | 0.84 | CHRNA7 (0.58) | CHRNA7CHRNB2CHRNA4HTR3AHTR3E | |
| SCHEMBL1542668 | 0.84 | CHRNA7 (0.58) | CHRNA7CHRNB2CHRNA4HTR3AHTR3E | |
| SCHEMBL1542646 | 0.84 | CHRNA7 (0.58) | CHRNA7CHRNB2CHRNA4HTR3AHTR3E | |
| SCHEMBL3844217 | 0.81 | CHRNA7 (0.55) | CHRNA7 | |
| SCHEMBL3846223 | 0.81 | CHRNA7 (0.55) | CHRNA7 | |
| Fumaric Acid SCHEMBL1542710 | 0.77 | CHRNA7 (0.50) | CHRNA7CHRNB2CHRNA4HTR3AHTR3E | |
| Fumaric Acid SCHEMBL1542521 | 0.77 | CHRNA7 (0.50) | CHRNA7CHRNB2CHRNA4HTR3AHTR3E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050137184-A1 | Fused bicycloheterocycle substituted quinuclidine derivatives | ABBVIE INC. | 2005-06-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050137184-A1 | Fused bicycloheterocycle substituted quinuclidine derivatives | CHRNA1, CHRNA7, CHRNA2 | CHRNA7 2/4885CHRNB2 12/4885CHRNA4 9/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.