Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.56 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.56 |
| ▸ | MAPT | P10636 | 4/20 | 0.51 |
| ▸ | LMNA | P02545 | 3/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.49 |
| ▸ | NPC1 | O15118 | 3/20 | 0.49 |
| ▸ | RAB9A | P51151 | 3/20 | 0.49 |
| ▸ | TP53 | P04637 | 3/20 | 0.49 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.49 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.49 |
| ▸ | RELA | Q04206 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | ESR1 | P03372 | 1/20 | 0.40 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.40 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10360988 | 0.95 | ALDH1A1 (0.56) | ALDH1A1CYP3A4MAPTLMNAKDM4E | |
| SCHEMBL1282665 | 0.94 | ALDH1A1 (0.55) | ALDH1A1CYP3A4MAPTLMNAKDM4E | |
| SCHEMBL9007847 | 0.89 | ALDH1A1 (0.68) | ALDH1A1CYP3A4MAPTLMNAKDM4E | |
| SCHEMBL10361043 | 0.87 | HSP90AA1 (0.52) | ALDH1A1CYP3A4MAPTLMNAKDM4E | |
| SCHEMBL10391870 | 0.84 | ALDH1A1 (0.68) | ALDH1A1CYP3A4MAPTLMNAKDM4E | |
| SCHEMBL1286469 | 0.81 | ALDH1A1 (0.57) | ALDH1A1CYP3A4KDM4EMEN1KMT2A | |
| SCHEMBL10545905 | 0.81 | MAPT (0.58) | ALDH1A1CYP3A4MAPTLMNAKDM4E | |
| SCHEMBL10550406 | 0.81 | ALDH1A1 (0.60) | ALDH1A1CYP3A4MAPTLMNAKDM4E | |
| SCHEMBL2128040 | 0.78 | MAPK1 (0.63) | ALDH1A1CYP3A4LMNAKDM4EMEN1 | |
| SCHEMBL1286485 | 0.78 | ALDH1A1 (0.57) | ALDH1A1CYP3A4MAPTKDM4EMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050203171-A1 | Oxathiincarboxamides | BAYER CROPSCIENCE AG (DE) | 2005-09-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050203171-A1 | Oxathiincarboxamides | MRPL21, ODC1, DDT | ALDH1A1 138/4885CYP3A4 901/4885MAPT 2229/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.