SCHEMBL647916

SCHEMBL647916

CC(=O)C(=O)OCc1ccccc1

nearest known ligand 0.70

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 6/20 0.70
TDP1 Q9NUW8 3/20 0.57
MAPK1 P28482 2/20 0.57
L3MBTL1 Q9Y468 2/20 0.57
SLC6A2 P23975 1/20 0.57
SLC6A3 Q01959 1/20 0.57
KMT2A Q03164 1/20 0.57
LMNA P02545 3/20 0.52
HCAR2 Q8TDS4 1/20 0.52
RAB9A P51151 2/20 0.49
NPC1 O15118 1/20 0.49
MAPT P10636 1/20 0.49
HPGD P15428 1/20 0.49
HTT P42858 1/20 0.49
MAOB P27338 1/20 0.49
CYP3A4 P08684 1/20 0.47
TSHR P16473 1/20 0.47
SMN1; SMN2 Q16637 1/20 0.47
CA12 O43570 1/20 0.47
CA1 P00915 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13234406 1.00 ALDH1A1 (0.70) ALDH1A1TDP1MAPK1L3MBTL1SLC6A2
SCHEMBL13234399 1.00 ALDH1A1 (0.70) ALDH1A1TDP1MAPK1L3MBTL1SLC6A2
SCHEMBL13234397 1.00 ALDH1A1 (0.70) ALDH1A1TDP1MAPK1L3MBTL1SLC6A2
SCHEMBL13234427 1.00 ALDH1A1 (0.70) ALDH1A1TDP1MAPK1L3MBTL1SLC6A2
SCHEMBL13234395 1.00 ALDH1A1 (0.70) ALDH1A1TDP1MAPK1L3MBTL1SLC6A2
SCHEMBL13234401 1.00 ALDH1A1 (0.70) ALDH1A1TDP1MAPK1L3MBTL1SLC6A2
SCHEMBL7965460 0.89 ALDH1A1 (0.58) ALDH1A1TDP1MAPK1L3MBTL1SLC6A2
SCHEMBL3846207 0.88 ALDH1A1 (0.70) ALDH1A1TDP1MAPK1L3MBTL1SLC6A2
SCHEMBL9397986 0.88 ALDH1A1 (0.70) ALDH1A1TDP1MAPK1L3MBTL1SLC6A2
SCHEMBL27144 0.87 ALDH1A1 (0.68) ALDH1A1TDP1MAPK1L3MBTL1SLC6A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 25569 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-122094660-A Composition in the form of an oil-in-water emulsion 2026-05-26 CN claimed
US-12630491-B2 Production of 2,2,4,4-tetramethylcyclobutane-1,3-diol from secondary alcohols and 2,2,4,4-tetramethylcyclobutanedione using homogeneous catalysts EASTMAN CHEMICAL COMPANY (US) 2026-05-19 US claimed
EP-4740733-A1 COMPOSITIONS OF ADJUVANTS AND COSOLVENTS FOR IMPROVING PENETRATION OF HERBICIDES AND/OR FERTILISERS THROUGH SURFACES OF ABOVEGROUND PARTS OF PLANT ORGANS. Uniwersystet Slaski w Katowicach (PL) 2026-05-13 EP claimed
CN-116568662-B Production of 2, 4-tetramethyl cyclobutane-1, 3-diol from secondary alcohol and 2, 4-tetramethyl cyclobutanedione using homogeneous catalyst 伊士曼化工公司 2026-05-12 CN claimed
WO-2026085839-A1 COMPOSITION AND METHOD FOR CARING FOR KERATIN MATERIALS L'OREAL (FR) 2026-04-30 WO claimed
EP-3760623-B1 TETRAHYDRO-PYRIDO[3,4-B]INDOLE ESTROGEN RECEPTOR MODULATORS AND USES THEREOF HOFFMANN LA ROCHE (CH) 2026-03-18 EP claimed
WO-2026040002-A1 COMPOSITION AND METHOD FOR CARING FOR THE SKIN L'OREAL (FR) 2026-02-26 WO claimed
US-20250353265-A1 METHOD FOR MAKING EMBEDDED HYDROGEL CONTACT LENSES ALCON INC (CH) 2025-11-20 US claimed
US-12391014-B2 Method for making embedded hydrogel contact lenses ALCON INC. (CH) 2025-08-19 US claimed
US-12384754-B2 Cocrystals of (1R,3S)-3-(5-cyano-4-phenyl-1,3-thiazol-2-ylcarbamoyl)cyclopentane carboxylic acid PALOBIOFARMA, S.L. (ES) 2025-08-12 US claimed
EP-0983228-A4 PROTEASE INHIBITORS SMITHKLINE BEECHAM CORP (US) 2002-08-07 EP claimed
EP-1067894-A2 PROTEASE INHIBITORS SmithKline Beecham Corporation (US) 2001-01-17 EP claimed
CN-1255119-A Protease inhibitors SMITHKLINE BEECHAM CORP (US) 2000-05-31 CN claimed
EP-0983228-A1 PROTEASE INHIBITORS SMITHKLINE BEECHAM CORPORATION (US) 2000-03-08 EP claimed
WO-1999059526-A2 PROTEASE INHIBITORS SMITHKLINE BEECHAM CORPORATION (US) 1999-11-25 WO claimed
WO-1998050342-A1 PROTEASE INHIBITORS SMITHKLINE BEECHAM CORPORATION (US) 1998-11-12 WO claimed
EP-0387058-A1 Process for preparing benzylpyruvic acids and esters MERCK & CO. INC. (US) 1990-09-12 EP claimed
US-4956490-A Process for preparing benzylpyruvic acids and esters MERCK & CO., INC. (US) 1990-09-11 US claimed
US-4481368-A Process for preparing α-keto-carboxylic acids from acyl halides ETHYL CORPORATION (US) 1984-11-06 US claimed
US-4481369-A VIA TRICARBONYL(TRIPHENYLPOSPHINE) COBALTATE ETHYL CORPORATION (US) 1984-11-06 US claimed