Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 6/20 | 0.49 |
| ▸ | CNR1 | P21554 | 2/20 | 0.49 |
| ▸ | USP2 | O75604 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | CHRM1 | P11229 | 3/20 | 0.43 |
| ▸ | HRH1 | P35367 | 3/20 | 0.43 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.42 |
| ▸ | LCK | P06239 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5851495 | 0.93 | ALDH1A1 (0.50) | CNR2CNR1USP2POLBALDH1A1 | |
| SCHEMBL6479330 | 0.79 | TAAR1 (0.61) | CNR2USP2POLBTAAR1 | |
| SCHEMBL12791633 | 0.76 | TAAR1 (0.61) | CNR2USP2POLBTAAR1 | |
| SCHEMBL3969006 | 0.76 | USP2 (0.61) | CNR2CNR1USP2POLBALDH1A1 | |
| SCHEMBL3969841 | 0.76 | CNR2 (0.53) | CNR2CNR1USP2POLBALDH1A1 | |
| SCHEMBL13196912 | 0.75 | TLR7 (0.62) | CNR2CNR1USP2POLBTAAR1 | |
| SCHEMBL13052920 | 0.73 | USP2 (0.52) | CNR2CNR1USP2POLBALDH1A1 | |
| SCHEMBL8022188 | 0.72 | USP2 (0.54) | CNR2CNR1USP2POLBATM | |
| SCHEMBL6461068 | 0.72 | ESR2 (0.54) | CNR2CNR1USP2POLB | |
| SCHEMBL5851500 | 0.71 | TAAR1 (0.60) | ALDH1A1GAATAAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6962938-B2 | Spiro-cyclic β-amino acid derivatives as inhibitors of matrix metalloproteases and TNF-α converting enzyme (TACE) | BRISTOL-MYERS SQUIBB PHARMA COMPANY (US) | 2005-11-08 | — | — | US | disclosed |
| US-6720329-B2 | ANTIINFLAMMATORY AGENTS | BRISTOL-MYERS SQUIBB PHARMA | 2004-04-13 | — | — | US | disclosed |