Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB2 | P07550 | 10/20 | 0.67 |
| ▸ | ADRB1 | P08588 | 7/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | HTR1A | P08908 | 1/20 | 0.50 |
| ▸ | THPO | P40225 | 1/20 | 0.50 |
| ▸ | BLM | P54132 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | NMUR2 | Q9GZQ4 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.50 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.50 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.50 |
| ▸ | ADRB3 | P13945 | 2/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Acetonitrile SCHEMBL11575978 | 0.95 | ADRB2 (0.61) | ADRB2ADRB1ALDH1A1HTR1ATHPO | |
| Acetonitrile SCHEMBL11576215 | 0.93 | ADRB2 (0.60) | ADRB2ADRB1ALDH1A1HTR1ATHPO | |
| SCHEMBL8855343 | 0.86 | ADRB2 (0.52) | ADRB2ADRB1ALDH1A1HTR1ATHPO | |
| SCHEMBL10909213 | 0.86 | ADRB2 (0.52) | ADRB2ADRB1ALDH1A1HTR1ATHPO | |
| SCHEMBL11094191 | 0.85 | ADRB2 (0.66) | ADRB2ADRB1HTR1ABLMKDM4E | |
| Bromide SCHEMBL8855307 | 0.85 | ADRB2 (0.51) | ADRB2ADRB1ALDH1A1HTR1ATHPO | |
| SCHEMBL6506682 | 0.84 | ADRB2 (0.59) | ADRB2ADRB1ADRB3 | |
| SCHEMBL10539169 | 0.82 | ADRB2 (0.60) | ADRB2ADRB1ADRB3 | |
| SCHEMBL9481583 | 0.82 | ADRB2 (0.62) | ADRB2ADRB1BLMSMN1; SMN2KDM4E | |
| SCHEMBL10889941 | 0.82 | ADRB2 (0.57) | ADRB2ADRB1ADRB3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005108381-A1 | SYNTHESIS AND USES OF SYNEPHRINE DERIVATIVES | SYNTECH (SSPF) INTERNATIONAL INC. (US) | 2005-11-17 | — | — | WO | disclosed |