Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 6/20 | 0.75 |
| ▸ | CHRM5 | P08912 | 3/20 | 0.75 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.75 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.75 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.75 |
| ▸ | CA12 | O43570 | 2/20 | 0.69 |
| ▸ | CA1 | P00915 | 2/20 | 0.69 |
| ▸ | CA2 | P00918 | 2/20 | 0.69 |
| ▸ | CA9 | Q16790 | 2/20 | 0.69 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.60 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.60 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.60 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.59 |
| ▸ | HPGD | P15428 | 1/20 | 0.59 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.59 |
| ▸ | LMNA | P02545 | 1/20 | 0.57 |
| ▸ | TSHR | P16473 | 1/20 | 0.57 |
| ▸ | DRD4 | P21917 | 1/20 | 0.55 |
| ▸ | DRD3 | P35462 | 1/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2930549 | 0.94 | SIGMAR1 (0.67) | SIGMAR1CHRM5ALDH1A1CHRM3MAPK1 | |
| SCHEMBL23612751 | 0.87 | SIGMAR1 (0.71) | SIGMAR1CHRM5ALDH1A1CHRM3MAPK1 | |
| SCHEMBL19034848 | 0.87 | SIGMAR1 (0.71) | SIGMAR1CHRM5ALDH1A1CHRM3MAPK1 | |
| SCHEMBL19636761 | 0.87 | SIGMAR1 (0.71) | SIGMAR1CHRM5ALDH1A1CHRM3MAPK1 | |
| SCHEMBL2929446 | 0.86 | SIGMAR1 (0.58) | SIGMAR1CHRM5ALDH1A1CHRM3MAPK1 | |
| Esaprazole SCHEMBL931007 | 0.86 | SIGMAR1 (1.00) | SIGMAR1CHRM5ALDH1A1CHRM3MAPK1 | |
| SCHEMBL27634646 | 0.86 | SIGMAR1 (0.67) | SIGMAR1CHRM5ALDH1A1CHRM3MAPK1 | |
| SCHEMBL10304524 | 0.86 | SIGMAR1 (0.67) | SIGMAR1CHRM5ALDH1A1CHRM3MAPK1 | |
| SCHEMBL11010870 | 0.86 | SIGMAR1 (0.91) | SIGMAR1CHRM5ALDH1A1CHRM3MAPK1 | |
| SCHEMBL1024404 | 0.85 | SIGMAR1 (1.00) | SIGMAR1CHRM5ALDH1A1CHRM3MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1997007117-A1 | 2-ACYLAMINOPROPANAMINES AS GROWTH HORMONE SECRETAGOGUES | ELI LILLY AND COMPANY (US) | 1997-02-27 | — | — | WO | claimed |
| US-20050100476-A1 | Chemical processing system and method | IMPERIAL COLLEGE OF SCIENCE TECHNOLOGY AND MEDICINE (GB) | 2005-05-12 | — | — | US | disclosed |
| EP-1322412-A1 | CHEMICAL PROCESSING SYSTEM AND METHOD | Imperial College of Science, Technology and Medicine (GB) | 2003-07-02 | — | — | EP | disclosed |
| WO-2002022251-A1 | CHEMICAL PROCESSING SYSTEM AND METHOD | IMPERIAL COLLEGE OF SCIENCE, TECHNOLOGY AND MEDICINE (GB) | 2002-03-21 | — | — | WO | disclosed |