SCHEMBL6479874

SCHEMBL6479874

O=C1C=CC2=C(CCCC2)CC1

nearest known ligand 0.36

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.36
GSK3A P49840 1/20 0.33
GSK3B P49841 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7627774 0.91 ALDH1A1 (0.36) ALDH1A1GSK3AGSK3B
SCHEMBL943110 0.81 GSK3A (0.46) ALDH1A1GSK3AGSK3B
SCHEMBL7338785 0.79 GSK3A (0.43) ALDH1A1GSK3AGSK3B
SCHEMBL9527717 0.76 GSK3A (0.46) ALDH1A1GSK3AGSK3B
SCHEMBL17477583 0.73 ALDH1A1 (0.58) ALDH1A1GSK3AGSK3B
SCHEMBL17477579 0.73 ALDH1A1 (0.58) ALDH1A1GSK3AGSK3B
SCHEMBL451440 0.72
SCHEMBL2600398 0.67
SCHEMBL29660517 0.64 GSK3A (0.47) ALDH1A1GSK3AGSK3B
SCHEMBL9333338 0.63 ALDH1A1 (0.32) ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1553170-A1 NOVEL CARBONYL REDUCTASE, GENE THEREOF AND METHOD OF USING THE SAME KANEKA CORPORATION (JP) 2005-07-13 EP claimed
EP-1553170-A1 NOVEL CARBONYL REDUCTASE, GENE THEREOF AND METHOD OF USING THE SAME KANEKA CORPORATION (JP) 2005-07-13 EP disclosed