Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LPAR1 | Q92633 | 4/20 | 0.44 |
| ▸ | MEN1 | O00255 | 4/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.40 |
| ▸ | SHMT1 | P34896 | 2/20 | 0.40 |
| ▸ | SHMT2 | P34897 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.39 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.39 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.39 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.39 |
| ▸ | MAOA | P21397 | 1/20 | 0.37 |
| ▸ | HTR2A | P28223 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.36 |
| ▸ | XIAP | P98170 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6473620 | 0.92 | LPAR1 (0.44) | LPAR1MEN1KMT2AGAAKDM4E | |
| SCHEMBL6480025 | 0.89 | GAA (0.44) | LPAR1MEN1KMT2ASHMT1SHMT2 | |
| SCHEMBL6474846 | 0.88 | MEN1 (0.42) | LPAR1MEN1KMT2ASHMT1SHMT2 | |
| SCHEMBL8657003 | 0.87 | SHMT1 (0.43) | SHMT1SHMT2LMNA | |
| SCHEMBL8906957 | 0.87 | SHMT1 (0.47) | MEN1KMT2ASHMT1SHMT2 | |
| SCHEMBL6475325 | 0.87 | MEN1 (0.41) | LPAR1MEN1KMT2ASHMT1SHMT2 | |
| SCHEMBL6483689 | 0.87 | KMT2A (0.41) | LPAR1MEN1KMT2ASHMT1SHMT2 | |
| SCHEMBL6474979 | 0.86 | LPAR1 (0.51) | LPAR1MEN1KMT2ASHMT1SHMT2 | |
| SCHEMBL6474884 | 0.85 | LPAR1 (0.52) | LPAR1MEN1KMT2ASHMT1SHMT2 | |
| SCHEMBL6473570 | 0.85 | LPAR1 (0.52) | LPAR1MEN1KMT2ASHMT1SHMT2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6939888-B2 | 1-H-3-arylpirrolidine-2,4-dione derivatives | BAYER AKTIENGESELLSCHAFT (DE) | 2005-09-06 | — | — | US | disclosed |
| US-6472419-B1 | 1-H-3-aryl-pyrrolidine-2, 4-dione derivatives as pest-control agents | BAYER AKTIENGESELLSCHAFT (DE) | 2002-10-29 | — | — | US | disclosed |