Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KAT8 | Q9H7Z6 | 7/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | RET | P07949 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | JAK2 | O60674 | 2/20 | 0.30 |
| ▸ | JAK1 | P23458 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6486743 | 0.93 | KAT8 (0.32) | KAT8RETJAK2JAK1 | |
| SCHEMBL6175126 | 0.90 | EIF2AK4 (0.37) | KMT2AL3MBTL1GAAJAK2JAK1 | |
| SCHEMBL6170568 | 0.84 | RET (0.31) | KAT8RETJAK2JAK1 | |
| SCHEMBL6169447 | 0.84 | EIF2AK4 (0.35) | KMT2ARETJAK2JAK1 | |
| Hydrochloric Acid SCHEMBL6169685 | 0.82 | KCNH2 (0.31) | — | |
| SCHEMBL6481640 | 0.82 | DPP4 (0.33) | KMT2ARET | |
| Trifluoroacetic Acid SCHEMBL6177905 | 0.79 | EIF2AK4 (0.35) | — | |
| SCHEMBL7506081 | 0.79 | SCN5A (0.38) | — | |
| SCHEMBL7501829 | 0.79 | SCN5A (0.38) | — | |
| SCHEMBL6169430 | 0.76 | EIF2AK4 (0.35) | KMT2ARETJAK2JAK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6900224-B2 | Antimicrobial quinolones, their compositions and uses | THE PROCTER & GAMBLE COMPANY (US) | 2005-05-31 | — | — | US | disclosed |
| US-20040038975-A1 | Antimicrobial quinolones, their compositions and uses | THE PROCTER & GAMBLE COMPANY | 2004-02-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040038975-A1 | Antimicrobial quinolones, their compositions and uses | QARS1, NQO2, Q6ZSR9 | KAT8 2673/4885KMT2A 4196/4885L3MBTL1 3861/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.