Biphenyl

Biphenyl

SCHEMBL6480056

Cc1ccccc1[SiH2]c1ccccc1C.c1ccc(-c2ccccc2)cc1

nearest known ligand 0.45

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.45
TSHR P16473 3/20 0.43
ACHE P22303 3/20 0.43
CYP1A2 P05177 2/20 0.38
CYP1A1 P04798 1/20 0.38
CYP1B1 Q16678 1/20 0.38
SLC22A2 O15244 1/20 0.37
SLC22A1 O15245 1/20 0.37
SLC22A3 O75751 1/20 0.37
SLC6A4 P31645 1/20 0.37
MAOA P21397 1/20 0.37
MAOB P27338 1/20 0.37
CYP2A6 P11509 1/20 0.37
CYP2B6 P20813 1/20 0.37
TNKS2 Q9H2K2 1/20 0.36
NPC1 O15118 2/20 0.35
RAB9A P51151 2/20 0.35
BRD4 O60885 1/20 0.35
HPGD P15428 1/20 0.35
SMN1; SMN2 Q16637 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2879034 0.89 TSHR (0.53) ALDH1A1TSHRACHECYP1A2CYP2A6
SCHEMBL4141599 0.87 TSHR (0.50) ALDH1A1TSHRACHECYP1A2CYP2A6
SCHEMBL21723001 0.87 CYP2A6 (0.41) ALDH1A1TSHRACHECYP2A6CYP2B6
SCHEMBL23700638 0.81 ACHE (0.39) ALDH1A1TSHRACHECYP2A6TNKS2
SCHEMBL2453373 0.80 TSHR (0.43) ALDH1A1TSHRACHECYP1A2CYP2A6
Biphenyl SCHEMBL27587661 0.78 ACHE (0.71) ALDH1A1TSHRACHECYP1A2SLC22A2
SCHEMBL2522936 0.77 TSHR (0.45) ALDH1A1TSHRACHECYP1A2CYP2A6
SCHEMBL29229144 0.76 TSHR (0.39) ALDH1A1TSHRACHENPC1RAB9A
Tannin Pyrogallol SCHEMBL1420025 0.75 TSHR (0.67) ALDH1A1TSHRACHECYP1A2CYP1A1
Biphenyl SCHEMBL10908521 0.75 ACHE (0.67) ALDH1A1TSHRACHECYP1A2SLC22A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20050238919-A1 Organic electroluminescent device FUJI PHOTO FILM CO., LTD. 2005-10-27 US claimed
US-9029541-B2 Binuclear metal complex, and organic electroluminescence element comprising same UBE INDUSTRIES, LTD. (JP) 2015-05-12 US disclosed
US-20130324733-A1 BINUCLEAR METAL COMPLEX, AND ORGANIC ELECTROLUMINESCENCE ELEMENT COMPRISING SAME UBE INDUSTRIES, LTD. (JP) 2013-12-05 US disclosed
EP-2647642-A1 BINUCLEAR METAL COMPLEX, AND ORGANIC ELECTROLUMINESCENCE ELEMENT USING SAME Ube Industries, Ltd. (JP) 2013-10-09 EP disclosed
CN-102775432-A Phosphorescent dye parent materials with tetrahedral structure, and application thereof in electroluminescent device UNIV JILIN 2012-11-14 CN disclosed
US-20050238919-A1 Organic electroluminescent device FUJI PHOTO FILM CO., LTD. 2005-10-27 US disclosed