Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | HSD11B1 | P28845 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.37 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6480423 | 1.00 | KMT2A (0.49) | KMT2AMAPK1HSD11B1ALDH1A1HPGD | |
| SCHEMBL892699 | 0.86 | KMT2A (0.57) | KMT2AMAPK1HSD11B1ALDH1A1HPGD | |
| SCHEMBL3289241 | 0.83 | KMT2A (0.48) | KMT2AMAPK1HSD11B1ALDH1A1HPGD | |
| SCHEMBL3289245 | 0.83 | KMT2A (0.48) | KMT2AMAPK1HSD11B1ALDH1A1HPGD | |
| SCHEMBL5629867 | 0.79 | KMT2A (0.48) | KMT2AMAPK1HSD11B1ALDH1A1HPGD | |
| SCHEMBL5629865 | 0.79 | KMT2A (0.48) | KMT2AMAPK1HSD11B1ALDH1A1HPGD | |
| SCHEMBL6480190 | 0.77 | KMT2A (0.47) | KMT2AMAPK1HSD11B1ALDH1A1HPGD | |
| SCHEMBL6480191 | 0.77 | KMT2A (0.47) | KMT2AMAPK1HSD11B1ALDH1A1HPGD | |
| SCHEMBL14177730 | 0.74 | ALDH1A1 (0.50) | KMT2AMAPK1HSD11B1ALDH1A1HPGD | |
| SCHEMBL14177728 | 0.74 | ALDH1A1 (0.50) | KMT2AMAPK1HSD11B1ALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050119231-A1 | Quinolone antibacterial agents | ELLSWORTH EDMUND L (US) | 2005-06-02 | — | — | US | disclosed |
| US-20050107423-A1 | Quinolone antibacterial agents | ELLSWORTH EDMUND L (US) | 2005-05-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050119231-A1 | Quinolone antibacterial agents | NQO2, MRPL21, TOP1 | KMT2A 4774/4885MAPK1 3325/4885HSD11B1 2578/4885 |
| US-20050107423-A1 | Quinolone antibacterial agents | NQO2, MRPL21, TOP1 | KMT2A 4774/4885MAPK1 3325/4885HSD11B1 2578/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.